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Showing 1 to 2 of 2 for “"High shear melt granulation"”.
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A novel solvent-free high shear technology for the preparation of pharmaceutical cocrystals
High shear melt granulation (HSMG) is an established technology for a production of densified granules. In this project, it was used as a novel solvent-free method for the preparation of cocrystals. Cocrystals produced by HSMG were compared to those prepared by Hot Melt Extrusion (HME) to …
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Optimization of granule size and tablet properties in a twin screw granulator: the influence of process and formulation parameters
… and other associated processing costs in wet granulation is a benefit of melt granulation. However, twin screw hot melt granulation is rarely applied in most industries. This work details the product characteristics and optimization from melt granulation of the model materials, calcium …