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Showing 1 to 20 of 30 for “"High Density Lipoproteins"”.
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ROLE OF HIGH DENSITY LIPOPROTEINS AGAINST PROSTATE CANCER
… poor prognosis and limited treatment options, highlighting the need for new therapeutic strategies. The tumor microenvironment (TME) contains pro-oxidant, pro-inflammatory mediators and lipids such as cholesterol and fatty acids, which sustain proliferation, survival, and angiogenesis. …
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Structure, Assembly, and Maturation of High -Density Lipoproteins
High-density lipoproteins (HDL) are protein-lipid particles that are involved in the transport of cholesterol in the blood. They are of great importance in the treatment of coronary heart disease as low levels of HDLs are a known risk factor for the development of arteriosclerosis. Little is known …
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Structure, Assembly, and Maturation of High-Density Lipoproteins
High-density lipoproteins (HDL) are protein-lipid particles that are involved in the transport of cholesterol in the blood. They are of great importance in the treatment of coronary heart disease as low levels of HDLs are a known risk factor for the development of arteriosclerosis. Little is known …
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The Role of High-Density Lipoproteins and Related Pathways in Alzheimer’s Disease
… ages. It has been firmly established that high plasma levels of high-density lipoprotein (HDL) protect against cardiovascular disease and accumulating evidence indicates that the beneficial role of HDL extends to the central nervous system. There are several important biological mechanisms …
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Spontaneous lipid transfers between low density lipoproteins and reconstituted high density lipoproteins
… important components in the metabolism of low density lipoprotein (LDL) and high density lipoprotein (HDL). Cholesterol spontaneously transfers from LDL to HDL; phospholipid transfer proceeds in the reverse direction. Reconstituted HDL (rHDL) particles were employed in this study. Cholesterol …
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The study of spherical high-density lipoproteins and the intermediates involved in their formation
High density lipoproteins (HDL), which are found as spherical particles in the circulation, contain a core of neutral lipids, mainly cholesterol esters and an outer shell of apolipoproteins, phospholipids, and cholesterol. Discoidal HDL, discovered in the plasma of patients deficient in lecithin …
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Phospholipid Transfer From Vesicles to High Density Lipoproteins, Catalyzed by Human Plasma Phospholipid Transfer Protein (Liposome)
Human plasma phospholipid transfer protein (PLTP) catalyzes the mass transfer of phosphatidylcholine (PC). Partial purification of PLTP yielded proteins with apparent M(,r) = 59,000 and 40,000 by SDS-PAGE. PLTP activity was measured by transfer of ('14)C L-(alpha)-dipalmitoyl PC from egg-PC …
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The influence of apolipoproteins on the interaction of hepatic lipase with high density lipoproteins / Neil J. Hime
… spherical, apolipoprotein-specific reconstituted high density lipoproteins. The results show that apolipoproteins have a major impact on these processes.
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The effects of Bios Life and exercise on total cholesterol, serum low-density lipoprotein, and high-density lipoproteins
… dietary fiber supplement, on serum lipoproteins and determine whether exercise accentuates this effect. Fifty male and female subjects (ages 30--60) participated in the study. Twenty-five subjects were exercising regularly in a supervised exercise program and the other twenty-five …
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Effect of Structure and Composition of Reconstituted High Density Lipoproteins on Phosphatidylcholine Transfer by Human Plasma Phospholipid Transfer Protein
Discoidal-reconstructed high density lipoproteins (rHDL) were used to study the effect of HDL substrates on phosphatidylcholine (PC) transfer by human plasma phospholipid transfer protein (PLTP) by changing the composition and size of rHDL. Sonicated egg-PC:cholesterol vesicles containing …
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A Characterization of the Effect of Apolipoprotein AII on the Structure and Function of Apolipoprotein AI in Reconstituted High Density Lipoproteins
High density lipoproteins (HDL) can be fractionated by immunoaffinity chromatography into two main subclasses: a fraction which contains apolipoprotein (apo) AI and apoAII, and a fraction which contains apoAI but not apoAII. The effect of apoAII on the structure and function of apoAI in …
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Isolation and Characterization of Blood Lipoproteins From Dairy Cows Fed Control or High Grain Diets (Lactation, Feeding, Lipids)
Lipoproteins from the plasma of three non-lactating Holstein cows were isolated using either preparative ultracentrifugation or gel filtration chromatography. Lipoprotein classes obtained by ultracentrifugation were very low density plus chylomicrons, low density, high density(,1), and high …
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tissue-specific role of ATP binding cassette transporter A1 in atherogenesis
… across the plasma membrane to combine with apolipoproteins, forming nascent high density lipoproteins (HDL), the precursor of mature plasma HDL. Mutations in ABCA1 cause Tangier disease, characterized by extremely low plasma HDL cholesterol (HDL-C) levels and widespread storage of cholesterol …
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A Study of the Relationship of Self-Reported Resistance Training to Lipid Profiles.
… weight, percent body fat, total cholesterol, low-density lipoprotein and triglycerides, as well as, a higher average of high-density lipoproteins. Two sample t-tests were performed to determine significance. It was determined that no significant difference existed between serum lipid profile …
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Factors affecting the binding of lecithin:cholesterol acyltransferase with interfacial substrates
The esterification of cholesterol on high density lipoproteins (HDL) catalyzed by lecithin:cholesterol acyltransferase (LCAT) maintains a gradient for cholesterol diffusion from cell membranes and atherosclerotic plaques and plays a critical part in the maintenance of cholesterol homeostasis. The …
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Supramolecular Architectures in Molecular Medicine: Visualizing and Manipulating the Structure of Protein-Lipid Surfaces
… fundamental interest to science and technology. Lipoproteins, a complex of protein and lipid, serve as the primary transporter of cholesterol and other lipids throughout the body. There is a direct correlation between the presence of certain lipoprotein species and the incidence of coronary …
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Inclusion of Olive or Coconut Oil in a High-Fructose High-Fat Diet Increases Liver Injury in a Pig Model of Pediatric NAFLD
… randomly assigned to receive 1 of 3 hypercaloric high-fructose high-fat (HFF) diets for 10 weeks: 1) lard (LAR; n=5 pens), 2) lard + olive oil (OLI, n=10), and 3) lard + coconut oil (COC; n=10). Additional pigs (BSL, n=4) were fed a eucaloric diet to establish baseline values. Animals were …
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A comparison of cardiac rehabilitation, social support, and stress management training in coronary artery bypass graft patients
… mean heart rate, cholesterol, triglycerides, high density lipoproteins, and the cholesterol/high density lipoprotein ratio. Psychological self-report measures included: the Beck Depression Inventory, the Spielberger State/Trait Anxiety Index, the Jenkins Activity Survey, and the Hassles and …
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Anti-diabetic properties of GUH
… fed a maintenance diet (MD) with tap water or a high fat diet (HFD) with sucrose solution for a period of twelve weeks. Thereafter a separate groups of animals were then treated with GUH at 5 different dose levels, metformin or rosiglitazone for twelve weeks. Food intake, liquid intake, weights, …
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