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Showing 1 to 2 of 2 for “"Hi-C technology"”.

  1. Physics of Self-assembly in Complex Matter

    This dissertation is based on my graduate research studying complex matter in multiple areas of biological physics. While the complex matter systems in each area differ vastly in scale and function, I use similar computational approaches on each to answer scientific queries about their structure …

    houston Repository record for Physics of Self-assembly in Complex Matter (opens in a new tab)

  2. SCL: A Lattice-Based Approach to Infer Three-Dimensional Chromosome Structures from Single-Cell Hi-C Data

    <p>In contrast to population-based Hi-C data, single-cell Hi-C data are zero-inflated and do not indicate the frequency of proximate DNA segments. There are a limited number of computational tools that can model the three-dimensional structures of chromosomes based on single-cell Hi-C data.</p> …

    usm Repository record for SCL: A Lattice-Based Approach to Infer Three-Dimensional Chromosome Structures from Single-Cell Hi-C Data (opens in a new tab)