Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"Heteromeric channel"”.
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Molecular characterization of GABA receptor subunits from the parasitic nematode Haemonchus contortus
… by several nematocides which target ion channels. We have identified two H. contortus ion channel genes, Hcounc- 49B and C that encode two GABA-gated chloride channel subunits. Electrophysiological analysis shows that the Hco-UNC-49B subunit forms a functional homomeric channel in Xenopus …
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The identification of novel cys-loop receptor genes in Dirofilaria immitis
… is emerging. Cys-loop ligand-gated ion channels are an untapped source for drug targets essential for nematode neurotransmission. This thesis presents the isolation and preliminary pharmacological characterization of three inhibitory D. immitis ion channels: GLC-2, GLC-4, and LGC-49. …
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ATGLR3.7 AS NEGATIVE REGULATOR OF ATGLR3.3 MEDIATED STRESS RESPONSES
… depend on the activity of the cation permeable channel Glutamate Receptor-Like 3.3 (GLR3.3), but the mechanisms regulating this crucial factor remain largely unknown. GLRs are homologous to the animals’ ionotropic glutamate receptor channels (iGluRs), which can form both homo and …
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Ion channel modulation during Chlamydia trachomatis development
… recruits the host inwardly rectifying K+ channel Kir6 to the inclusion membrane from early in the infection cycle. Channel recruitment was most prevalent in stages of the C. trachomatis infection cycle when RB predominate, with Kir6 recruitment gradually diminishing in correspondence with …