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Showing 1 to 5 of 5 for “"Heterocyclic chemistry."”.
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The synthesis and structural characterisation of novel 4- and 5- membered nitrogen heterocycles derived from azoacetates
… of phenylazo compounds in the area of medicinal chemistry has largely been restricted to derivatives of primary aromatic amines. This has been due, in the most part, to a perceived view that azo compounds not containing two aromatic groups are unstable. The syntheses of a number of novel …
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Novel Polycyclic Benzannulated Indole Scaffolds via Indole Aryne Cycloaddition, Pd (0)-Catalyzed Cross-coupling and ROM/RCM methodologies: Their Applications to Library Development and Drug Discovery
… of Keith R. Buszek, Ph.D., Professor of Chemistry, University of Missouri-Kansas City. Heterocyclic chemistry is one of the most valuable sources of novel compounds with diverse biological activity. The indole nucleus for instance, is an important element of many natural and synthetic …
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Addressing the ongoing threat of antimicrobial resistance: synthetic investigations of novel amicetin and B-lactam antibiotics
… (chemotherapy), AMR, -lactam antibiotics, heterocyclic chemistry, and green chemistry techniques such as organocatalysis and visible-light photocatalysis, which were utilized to synthesize the relevant compounds described in this study. Chapter 2 provides background on the natural …
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1,1-enediamines and β-substituted enamines in heterocyclic synthesis
The work in this thesis mainly deals with l,l-enediamines and ~ -substituted enamines (push-pull olefines) and their reactions, leading to the formation of a number of heterocycles. Various ~-substituted enamines were prepared by a 'one pot synthesis' in which a l,l-enediamine presumably acts as an …
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ADVANCES IN THE DIRECTED ORTHO METALATION, SUZUKI-MIYAURA CROSS COUPLING, AND RING-OPENING REACTIONS OF INDAZOLES. SYNTHESIS OF LUMINESCENT ACRIDINE AND NOVEL INDAZOLE-BASED OXAZABORINES
… led DoM into the modern age of synthetic organic chemistry. Chapter one of this thesis begins with a brief review of traditional approaches for the carbon and nitrogen functionalization of indazoles and the reactivity challenges faced therein. This is followed by a comprehensive review of current …