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Showing 1 to 12 of 12 for “"Hesperidin"”.
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Biopharmaceutic and Pharmacokinetic Evaluation of Hesperidin and Hesperetin for Ocular Delivery
The bioflavonoid hesperidin and its aglycone hesperetin are promising candidates for the treatment of diabetic retinopathy and diabetic macular edema because of their pharmacological properties. The objective of this project was to characterize the biopharmaceutic and pharmacokinetic …
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Protective Effects of Yuzu and Its Component against Cardiovascular Disease
… a number of cardioprotective ingredients such as hesperidin. However, no study has proved whether yuzu can prevent LV remodeling. The aim of this study was to determine the effects of yuzu on HF and its potential impact on the LV remodeling process after MI and platelet aggregation. In this study, …
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Studies on the mechanism of action of the bioflavonoid Hesperidin methyl chalcone in causing vascular and intestinal smooth muscle to relax
… mechanisms of action of the bioflavonoid, hesperidin methyl chalcone (HMC), in causing smooth muscle to relax. The term bioflavonoid refers to several compounds that can be extracted from the mesocarp of citrus fruits. They have been the subject of investigation and controversy since 1936. …
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Genotoxic effects of a novel form of Gold Nanoparticles loaded with Hesperidin on head and neck cancer lymphocytes compared to effects from healthy control lymphocytes and Squamous cell Carcinoma of Maxillary sinus
… of gold nanoparticles (AuNPs) conjugated with hesperidin (Hsp) as a targeted drug delivery system. AuNPs are ideal for loading different drugs and delivering them to targets sites due to their stability, small size, substantial surface area, non-cytotoxic and inert nature. Hsp is a naturally …
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Genotoxic effects of a novel form of Gold Nanoparticles loaded with Hesperidin on head and neck cancer lymphocytes compared to effects from healthy control lymphocytes and Squamous cell Carcinoma of Maxillary sinus
… of gold nanoparticles (AuNPs) conjugated with hesperidin (Hsp) as a targeted drug delivery system. AuNPs are ideal for loading different drugs and delivering them to targets sites due to their stability, small size, substantial surface area, non-cytotoxic and inert nature. Hsp is a naturally …
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ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΩΝ ΧΗΜΙΚΩΝ ΣΥΣΤΑΤΙΚΩΝ ΤΩΝ ΦΥΛΛΩΝ ΤΟΥ ΦΥΤΟΥ CYNARA SCOLYMUS L.
… LUTEOLIN-7-DIGLUCOSIDE, RUTIN, HESPERIDIN, HESPERITIN, QUERCETIN. MINERAL ELEMENTS WERE ALSO DETECTED BY NETRONIC ACTIVATION (BR, FE, RD, NI, CR, SB, CO, SC, NA AND CL). FREE AMINO-ACIDS WERE ALSO DETECTED.
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A study of the metabolism and metabolomics of polyphenols using isolated rat hepatocytes and liquid chromatography-high resolution mass spectrometry
… p-coumaric acid and the flavonoids quercetin and hesperidin. The products formed by enzymatic transformation were characterised by liquid chromatography in combination with high resolution mass spectrometry. This was followed by extraction of the data with Sieve software and identification of the …
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Phytochemical, Chemopreventive and Antimalarial Activity Evaluation of Five Selected Medicinal Plants from the Cameroonian Flora
… mass spectrometry. Crotonolins A-D, skimmianine, hesperidin and myrtopsine were identified as potent chemopreventive compounds with fold induction greater than 2. None of the isolated compounds demonstrated any inhibition of haem polymerisation. This study generated the first phytochemical report …
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In vivo human acute cardiovascular effects of dietary flavanones – underlying mechanisms of action and impact of flavanone metabolism
… interventions (in random order): orange juice (hesperidin dose: 320 mg) or control, whereby both were matched for sugar and vitamin C. Markers of CVD risk and plasma concentrations of previously identified and novel flavanone / phenolic metabolites were simultaneously assessed at baseline and 5 …
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The Effects of Onion and Yuzu Extracts against Ischemia/Hypoxia-Induced Dysfunction of Blood-Brain Barrier
… (Quer), as well as yuzu extract (YE) and hesperidin (HSP) prevented brain ischemia-induced brain edema in dose-dependent manners. Evans blue extravasation in the ischemic hemisphere of the mouse brain was also significantly reduced by treatment with the four materials. In addition, they …
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Investigating the modulation of oral drug absorption using in vitro models
… (non-grapefruit) flavone derivatives tested, hesperidin, found in orange juice, had no significant effect, kaempferol and rutin also had no effect while genistein significantly inhibited p-glycoprotein (results that support previous studies). Hydroxycinnamic acids had no effect on …
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Dry milling characteristics and polyphenolic contents of adapted colored corn varieties and polyphenol extraction by combining deep eutectic solvents and ultrasound
… caffeic acid, ferulic acid, gallic acid, hesperidin, and chlorogenic acid, the highest values being 3.29, 1.72, 0.63, 15.18, and 5.23 mg/g pericarp, respectively. Finally, epicatechin, naringin and kaempferol concentrations of 102.73, 19.93, and 1.55 mg/g pericarp, respectively, were …