Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Hereditary nonpolyposis colorectal cancer (HNPCC)"”.
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Mutational analysis of the DNA mismatch repair genes, hMLH1 and hMSH2, in South African colorectal cancer patients
Colorectal cancer (CRC) is one of the most common forms of neoplasia in Western populations but is uncommon in sub-Saharan Africa. In developing countries such as South Africa, differences in lifestyles and environment exist between the various population groups. These differences and the diverse …
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Enhancement of Dicer as a personalized anticancer strategy
… of many disease states, including most forms cancer. A global downregulation of miRNA processing is common among cancers and has been shown to drive tumorogenesis. This global downregulation of miRNA biogenesis is caused by the disruption of key enzymes in the miRNA biogenesis pathway like …