Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Hepatocarcinoma"”.
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Análisis de la implicancia de los miARN en el hepatocarcinoma aplicando minería de texto
… de diferentes publicaciones, relacionadas con el hepatocarcinoma (HCC) y los miARN. A partir de acá se han obtenido genes que estarían implicados con esta enfermedad, miARN que juegan un papel importante y mutaciones que podrían conducir a la formación del HCC . El análisis realizado se visualiza …
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Terapia locorregional combinada en pacientes cirróticos con hepatocarcinoma atendidos en un centro de referencia en Colombia entre 2020-2024
Introducción: En hepatocarcinoma, las terapias TACE y ablación tienen eficacia limitada en monoterapia. Evidencia reciente sugiere que combinadas son seguras, potencian ventajas de cada una superando las limitaciones y amplían el efecto, especialmente para lesiones grandes o múltiples. Métodos: …
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Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver …
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Enfermedad hepática asociada a Fontan: caracterización de casos en hospital de cuarto nivel en Bogotá, Colombia
… en la mortalidad, especialmente si se asocia con hepatocarcinoma, lo que subraya la importancia de una detección temprana y un seguimiento adecuado. Objetivo: Describir las características clínicas, imagenológicas e histopatológicas de pacientes con FALD en nuestra institución. Métodos: Se realizó …
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Developing disease-state liver models to determine the effects on brain function in vitro
… to modulate the response of hepatoids and hepatocarcinoma to exogenous factors. Chapter 2 investigates how the morphology and functionality of the zebrafish liver is degraded by endocrine disrupting chemicals, such as estrogen and bisphenol-A. Chapter 3 explores methods for developing a …
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Expressão e análise de atividade enzimática da deubiquitinase USP2a recombinante
… estão presentes em diversas patologias, como o hepatocarcinoma e câncer de próstata, sendo vista como um possível alvo terapêutico. Entretanto, até o momento, nenhum inibidor seletivo dessa proteína é conhecido. Uma das alternativas para a busca de inibidores está na possibilidade em realizar a …
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Metabolic Manipulation of Glutathione as an Anticancer Therapeutic Target
… H2O2, yet maintained glutathione. HepG2 hepatocarcinoma cells, cells associated with fatty-acid stimulated disease progression, increased cell growth with coordinated increases in glutathione following palmitoylcarnitine. This dissertation considered recent evidence that suggests combined …
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Genetic Effect of MBL2 Polymorphisms in Patients with Diisocyanate-induced Occupational Asthma
… containing -554G compared to the -554C in human hepatocarcinoma cell (Hep3B) (P=0.002). EMSA showed that a -554G probe produced a specific shifted band compared to a -554C probe. CONCLUSION: These findings suggest that MBL2 ht2 [CAG] was significantly associated with the phenotype of DI-OA and …
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Análisis obsevacional para evaluar la eficacia y seguridad de los mTORi en la esfera oncológica en el paciente trasplantado hepático
… hepatic transplantation due to immunosuppressed hepatocarcinoma with mTOR inhibitors) and controls (immunosuppressed with calcineurin inhibitors), analyzing the rate of recurrence and cumulative survival. Patients: 392 patients were selected, analyzing cases and controls in two groups: patients …
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Der Metabolismus der Tocopherole und Tocotrienole
… γ-Tocotrienol eine cytotoxische Wirkung auf die Hepatocarcinoma-Zelllinie HepG2 entfalten kann, indem durch die Aktivierung der proteolytischen Caspase 3 die Induktion des programmierten Zelltodes (Apoptose) ausgelöst wird. Abschliessend lässt sich festhalten, dass der Körper lediglich das …
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Making In Utero Gene Therapy Safer and More Efficient: A First Step Towards Clinical Realization
… activated GFP-expression primarily in human hepatocarcinoma cells (HepG2) in vitro, indicating that this system could be used to achieve targeted transduction of human hepatocytes. Also, upon transfection with the plasmid construct for the first vector, sheep bone marrow mesenchymal stem …
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Experiences of injecting drugs, alcohol use and hepatitis C in Merseyside: Barriers to hepatitis C support
… hepatitis C such as end stage liver disease or hepatocarcinoma. The World Health Organization’s target to eliminate viral hepatitis as a major public health threat by 2030, has led to calls for action to increase access to hepatitis C testing and treatment. To increase uptake of testing and …
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Toxicology and herb-drug interaction of selected anti-hypertension plants used by lay persons in Northern KwaZulu-Natal (South Africa)
… assay (BSLA), Ames test and MTT assay (human hepatocarcinoma cell line HepG2/C3A)]. The toxicity interaction of the plant combination was evaluated using the sum of fractional inhibitory concentration (ΣFIC). Herb-drug interaction was performed on the aqueous extracts of the 13 medicinal …
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Protective effect of dietary antioxidants and plant extracts on acute inflammation and hepatotoxicity in vitro
… experiments were performed in vitro using human hepatocarcinoma cell line (HepG2). Additionally the antioxidant activity was measured by TEAC and FRAP assays, phenolic content was measured by Folin–Ciocalteu and characterized by HPLC. Moreover, the microheterogeneity of TTR was detected using …