Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Hepatocarcinogenesis"”.
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Targeting LGALS3 to treat steatotic liver disease and hepatocarcinogenesis
Non-alcoholic fatty liver disease (NAFLD), recently renamed as Metabolic dysfunction-associated steatotic liver disease (MASLD), is the leading cause of chronic liver disease (CLD) and liver-related morbidity and mortality worldwide. NAFLD, characterized by hepatic fat accumulation and coexisting …
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Uncovering the role of bile acid signaling in facilitating sex differences during hepatocarcinogenesis and liver metabolism
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01
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Hepatitis C Virus-Induced Hepatocellular Carcinoma: Cancer Stem Cell and Gene Therapy
… focused on finding mechanism (s) of HCV-induced hepatocarcinogenesis and devising novel means to combat the HCV infection.</p> <p>Herein, we have shown that long-term HCV expression results in the acquisition of cancer stem-like cells (CSCs) traits in liver derived cell lines. These traits …
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The role of neurofilament-light polipeptide (NEFL) in the onset and progression of hepatocellular carcinoma
… in the Resistant-Hepatocyte (R-H) rat model of hepatocarcinogenesis. Results: microarray analysis and qRT-PCR analysis showed that the expression of NEFL was strongly up-regulated at all stage of the multistep process of hepatocarcinogenesis, including the very early ones, in particular NEFL …
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Identification of Differentially Expressed Genes in a Rat Unilateral Ureteral Obstruction Model
… member 13 등 15개의 유전자가 UUO에서 발현이 증가 하였고, Gene for hepatocarcinogenesis-related transcription factor와 Superoxide dismutase 1, 그리고 Similar to myosin-VⅡb 3개의 유전자가 CUK에 비해 유의하게 발현이 감소했음을 확인하였다. 본 연구에서 확인된 유전자들의 발현 변화가 실존하는지에 대한 검증이 시행되어야 하며, 검증된 유전자들이 신부전에서 어떠한 역할을 할 것인지에 대한 연구가 필요할 것이다.
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Role of Hydroxy acid oxidase 2 (Hao2) in hepatocellular carcinoma
… to be the precursor of HCC in this model of hepatocarcinogenesis. Western blot analysis showed Hao2 down-regulation also at protein level. To determine whether this down-regulation is a general phenomenon in liver tumorigenesis or is specific only for rat liver, we analyze the expression of …
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Reduction of tumorigenesis in androgen receptor overexpressed Huh7 cells through TGF-β induced cellular senescence phenotypes
… its receptor (AR) are significantly related with hepatocarcinogenesis both in human and animals, however, the level of AR in hepatoma is variable and their exact effects are still poorly explained. Therefore, we investigated the role of androgen receptor (AR) in HCC development. METHOD: To …