Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 499 for “"Hepatitis"”.
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Einfluss von Immunsuppression auf Hepatitis C-assoziierte Immunphänomene und Hepatitis C-Quasispezies
Eine chronische Hepatitis C Infektion geht mit vielfältigen Autoimmunphänomenen einher. Deren klinische Bedeutung, sowie die Auswirkungen der HCV-assoziierten Kryoglobulinämie und der Komplementaktivierung auf die Transplantatfunktion bei nierentransplantierten Patienten wurden in dieser Arbeit …
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Hepatitis B and hepatitis C virus in an antenatal population : an epidemiological study
… was therefore conducted of the epidemiology of hepatitis B and hepatitis C infection in women. In addition, women were asked about their experience with antenatal testing. A total of 516 women participated in the survey, of these 479 (95%) women had been tested for HCV antibodies .The prevalence …
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"Constructing" Hepatitis C in Philadelphia
This research explores how the CDC Hepatitis Epidemiology Investigation Team at the Philadelphia Department of Public Health (PDPH) constructs Hepatitis C (HCV) in the public and medical discourse through their monitoring and education activities. Data in the form of field notes and ethnographic …
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Detection of Mouse Hepatitis Virus
Mouse hepatitis virus (MHV) is a common infection in a large number of laboratory mouse colonies and is known to interfere with research results. Serology testing is a good method of detecting the historical presence of MHV, however, it cannot detect when the mouse is currently shedding the …
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Experiences of injecting drugs, alcohol use and hepatitis C in Merseyside: Barriers to hepatitis C support
Hepatitis C is a blood borne virus affecting the liver. In the UK, approximately 214,000 people are infected with the hepatitis C virus. Hepatitis C disproportionally affects marginalised populations and in the UK sharing equipment used to inject drugs is the main risk factor for hepatitis C …
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Immunomodulation in Adenovirus-Induced Viral Hepatitis
… infection. The clinical outcomes in viral hepatitis can range from complete pathogen clearance and recovery of liver function to failure to contain the infection and loss of liver function. Because hepatotropic viruses are one of the major etiologic causes of morbidity and mortality …
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Immune reactions in acute viral hepatitis
viii, 122 leaves
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Characterising the immunopeptidome in hepatitis B
Characterising the immunopeptidome in hepatitis B Hepatitis B (HBV) is the leading cause of hepatocellular carcinoma (HCC) worldwide. There is presently no cure for HBV, and treatment options aim to reduce the risk of liver related complications and HCC. Immunotherapies have not been successful in …
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Initial Stages of Hepatitis B Virus Replication
… in Various Stage of DNA Replication Inside of hepatitis B virus (HBV) core particle, pgRNA is reverse transcribed by HBV DNA polymerase into minus-strand DNA and pregenomic RNA (pgRNA) is degraded concomitantly by RNase H activity of DNA polymerase. Then, plus-strand DNA is synthesized to …
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Health Utilities in People with Chronic Hepatitis C
Background: Hepatitis C virus infection is associated with reduced quality of life. One way to measure the quality of life of hepatitis C patients is using health utilities. Health utilities provide insight into not only the state of a patient’s health but also the strength of preference for that …
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Patterns of Selection In Hepatitis C and Hiv
<p>Viruses, such as Hepatitis and HIV, are able to evade the host immune responses they provoke and often lead to chronic infections and even death. Global estimates reveal that 130 million people are infected with Hepatitis C, while the number of people living with HIV/AIDS is 33.4 million. The …
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Molecular Mechanisms of Hepatitis C Virus- Associated Steatosis
Hepatitis C virus (HCV) infects millions of people worldwide and is one of the leading causes of liver damage. Infection with HCV is strongly correlated with an increased risk of steatosis, or fatty liver disease, which is caused by a build-up of fat deposits in hepatocytes. All genotypes of HCV …
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The Multifunctional Capsid Gene of Hepatitis C Virus
<p>In populations worldwide, the Hepatitis C Virus displays great diversity. The capsid gene, however, is remarkably conserved and this has led to predictions of RNA secondary structure and an overlapping, alternative reading frame (ARF). We investigated a role of the ARF in HCV infection, by …
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Molecular Mechanisms of Protection from Hepatitis C Infection
Hepatitis C virus (HCV) infection is a major global health burden affecting 1-2% of the world’s population. The majority of infected individuals will develop chronic infection and are at risk of cirrhosis and hepatocellular carcinoma. There is currently no preventative vaccine available for HCV. In …
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Biological Functions of Intracellular Hepatitis B e Antigen
The function(s) of the intracellular form of HBeAg, previously reported as the preCore protein intermediate (p22) without the N-terminal signal peptide, remains elusive. Here, we propose to elucidate the translocation of p22 during its formation from endoplasmic reticulum (ER) to cytosol, how it …
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T-lymphocyte senescence and hepatitis C virus infection
Hepatitis C virus (HCV) infection is a leading cause of cirrhosis and hepatocellular carcinoma. The degree of fibrosis progression and treatment-related outcomes are critically dependent on the age of the infected individual. Progressive ageing is associated with a decline in the efficacy of …
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Integrating Health Psychology into Hepatitis C treatment: a self-efficAcy intervention to reDuce injecting risk behAviour and hePatitis c reinfecTion rates (ADAPT)
… drugs (PWID) is a significant risk factor for hepatitis C virus (HCV) infection. Self-efficacy has been shown to be associated with injecting risk behaviour. The risk of HCV re-infection in people who inject drugs (PWID) treated for HCV remains high when sharing of injecting equipment continues …
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