Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Heparin-binding proteins."”.
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Innovative Purification Protocol for Heparin Binding Proteins: Relevance in Biopharmaceutical and Biomedical Applications
<p>Heparin binding (HB) proteins mediates a wide range of important cellular processes, which makes this class of proteins biopharmaceutically important. Engineering HB proteins could bring many advantages, but it necessitates cost effective and efficient purification methodologies compared to the …
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Cytotoxic Activity of Non-Specific Lipid Transfer Protein (nsLTP1) and Proteomic Evaluation of Heparin-Binding Proteins from Ajwain (Trachyspermum ammi) Seeds
… in Bcl-2, Survivin, EGFR, and VEGF Proteins. The CD analysis showed a significant proportion of α-helical structure, indicating nsLTP1 has the thermostable property. In serum, nsLTP1 showed a slow degradation rate, indicating high stability with a half-life of ⁓ 8.4 h. Our results …
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Identification of seminal proteins related to fertility of bulls
… conducted to determine the chemical identity of heparin binding proteins in semen that are related to fertility of bulls. The first study describes the isolation and identification of a 31,000 dalton fertility-associated antigen (FAA). FAA was found to have significant primary structure homology …
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The characterisation of the cell surface of Staphylococcus aureus in the search for new therapeutic targets
… cell receptors, a better understanding of which proteins are displayed on the cell surface is required. This dissertation presents an analysis of the surface proteome of S. aureus and describes several potential novel adhesins. Enzymatic cell shaving and surface protein biotinylation were used to …
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Expression and Purification of Unlabelled and Isotopically Labelled Human Fibroblast Growth Factor-1 and its Receptor Relevance in Cancer Research
… The FGF family consists of 23 different heparin-binding proteins. One of the most intensively studied members is human FGF-1 (hFGF-1) because of its critical role in the formation of blood vessels and cell proliferation in some types of cancer. The biological activities of FGFs are …
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Toxin-like proteins in the venom of Drosophila parasitoids
… are largely unknown. Some of their venom proteins have been shown to be important in suppressing host defense. Here, we report that Ganaspis brasiliensis, a parasitoid of D. suzukii survives well on Drosophila yakuba, a host species with a strong cellular immunity, and infected flies are …
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Synthesis and application of specifically sulfated carbohydrates containing methacrylate functionality
… to investigate the interactions of ligands and proteins. This led us to another direction taken by this research project to use computational techniques to determine possible interactions of our final sulfated polymers with heparin binding proteins (HBPs) such as fibroblast growth factor (FGF). …