Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Hemorrhagic fever virus"”.
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Vaccine Development Strategies for Crimean-Congo Hemorrhagic Fever Virus and its Tick Vector
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne bunyavirus with an extensive geographic range and complex ecology. Ticks within the Hyalomma genera are the primary vector and reservoir of the virus and maintain the virus through a cryptic tick-vertebrate-tick cycle in nature. However, …
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Studying the biology of, and developing countermeasures to, a tick-transmitted hemorrhagic fever virus
Crimean-Congo hemorrhagic fever (CCHF) is one of the world’s most medically relevant tick-borne viral diseases. The CCHF virus (CCHFV) is transmitted in seasonal cycles among ticks and animals and is endemic to the Eastern hemisphere. Severe disease may develop with outbreak case fatality rates up …
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Papel de las aves en la dispersión de garrapatas y microorganismos que vehiculan
… Borrelia, Rickettsia and Spiroplasma) and viruses (Crimean-Congo hemorrhagic fever virus, Flavivirus, Phlebovirus, Coltivirus and Orbivirus) using molecular biology techniques. In these studies, ticks belonging to five species (Haemaphysalis punctata, Hyalomma marginatum, Ixodes arboricola, …
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The production of a Crimean-Congo haemorrhagic fever virus diagnostic antigen in plants
Crimean-Congo Hemorrhagic Fever (CCHF) is a highly infectious, life threatening disease, caused by the Crimean-Congo Hemorrhagic Fever Virus (CCHFV), a nairovirus that forms part of the Bunyaviridae family. CCHFV has a case fatality rate of approximately 40%. Current diagnostic methods for CCHFV …
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Biophysical Characterization of the vOTU Proteases from the CCHF and Dugbe Nairoviruses
… domain protease superfamily (vOTU) from nairoviruses, and the structural reasons for their specificities. The vOTU from the Crimean-Congo Hemorrhagic Fever Virus (CCHFV) has been implicated in the down-regulation of the innate immune response through its ability to cleave post-translational …
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Thioaptamers Targeting Dengue Virus Type-2 Envelope Protein Domain III
The Dengue Virus Type-2 (DENV-2) is an arbovirus that belongs to the family of Flaviviridae, genus Flavivirus. It includes Dengue virus (DENV) types 1-4, West Nile virus, Langat virus, Omsk hemorrhagic fever virus and others that cause encephalitic or hemorrhagic disease. DENV binds the cell …
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Species Preference of Viral Deubiquitinating Proteases Toward ISG15 Through Structural and Enzymatic Characterization
… enzymes (DUBs) are expressed by a range of RNA viruses. Viral OTUs (vOTUs) are found in nairoviruses such as Crimean Congo Hemorrhagic Fever virus (CCHFV), Nairobi sheep disease virus (NSDV), the Erve virus (ERVEV), and the Dugbe virus (DUGV), as well as in the areterivirus Porcine Reproductive …
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Discovering LC3-interacting region (LIR) motifs in hemorrhagic fever viruses: Implications for host autophagy and viral replication.
Hemorrhagic fever viruses (HFVs) pose significant global health and economic burdens, yet limited FDA-approved therapeutics exist to combat their spread. Determining alterations in host processes during infection can enhance our understanding of viral replication and lead to potential host-based …