Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Hematopoietic stem cell transplant"”.
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The diversity of participants in clinical trials involving allogeneic hematopoietic stem cell transplant recipients
… in clinical trials involving allogeneic stem cell transplant recipients matched the diversity of the actual allogeneic recipient population overall. It is important that clinical trials study new therapies in a population that represents characteristics of the overall treatment population …
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PATTERN OF INNATE IMMUNITY IN PATIENTS AFFECTED BY MYELODYSPLASTIC SYNDROME (MDS) EITHER BEFORE ANDAFTER HEMATOPOIETIC STEM CELL TRANSPLANT (HSCT)
… the clonal proliferation of myelodysplastic cells and the trajectories of evolution of MDS with distinct clinical phenotypes. However, the definite pathogenetic mechanism of MDS is still not fully clarified, hindering the clinical decision-making process. Indeed, frontline pharmacological …
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The Effects of Pre-Transplant Music Therapy on Distress, Quality of Life, Pain, Anxiety, Mood, and Pain Medication Use for Patients Undergoing Hematopoietic Stem Cell Transplant
… trial was to determine the effects of pre-transplant music therapy on distress, pain, anxiety, mood, quality of life (QOL), and pain medication use during the preparation period for hematopoietic stem cell transplant (HSCT). Distress, the primary outcome, was measured via the Distress …
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Exploring the effect of caregiver support on psychological distress in stem cell transplant patients
… social support on psychological distress in stem cell transplant recipients during the first 90 days post-transplant. Despite advancements in hematopoietic stem cell transplant (HSCT) techniques, recipients often experience severe psychological distress due to the invasive nature of the …
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Assessing Patient Attitudes to ward Genetic Testing For Hereditary Hematologic Malignancy
… treatment, and donor selection for hematopoietic stem cell transplant. No studies have examined leukemia patients’ attitudes toward genetic testing for HHM. This study aimed to assess leukemia patients’ attitudes toward genetic testing and elicit current perceived distress due to a …
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Fc Gamma Receptors Facilitate Antigenic Modulation of LILRB4 and Function as Predictive Biomarkers in Acute Monocytic Leukemia
… cytotoxic chemotherapy as a bridge to hematopoietic stem cell transplant (HSCT). Even patients who achieve remission commonly relapse. This population of patients would greatly benefit from precision-targeted therapies but currently there are none approved for monocytic AML.</p> …
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Bilirubin Nanoparticle As An Anti-Inflammatory Therapy For Graft Versus Host Disease
… donor lymphocytes is a fatal complication of hematopoietic stem cell transplant (HSCT). Myeloablative conditioning regimen, consisting of chemotherapy and/or radiation, given prior to HSCT can cause tissue damage. This non-specific tissue damage triggers cross-presentation of alloantigens to …
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Understanding and Exploiting Viral Protein US28 During Human Cytomegalovirus Latency
… HCMV establishes latency in specific cell types following primary infection, and reactivates periodically during the lifetime of the host. One important site of HCMV latency is early myeloid lineage cells, including hematopoietic progenitor cells and monocytes, in which the critical …
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Adesão ao tratamento farmacológico no pós-transplante de células-tronco hematopoéticas
Introduction: Post-hematopoietic stem cell transplantation is a period in which adherence to pharmacological treatment is crucial to prevent complications such as graft-versus-host disease and graft failure. Therefore, the following research questions were formulated: What is the degree of …
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Cardiotoxicity In Hematologic Stem Cell Transplant: Keeping The Beat
<p>Abstract</p> <p>The number of hematopoietic stem cell transplants (HSCT) performed in the U.S. and worldwide is increasing. Cardiac events have been well described in HSCT, and incidence and type of cardiac events have not changed over recent decades. This study adds to the body of evidence in …
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Pediatric Oncology and Bone Marrow Transplant ICU Patients in Children’s and General Hospitals
Pediatric oncology and hematopoietic stem cell (HCT) care in the US is increasingly provided at children’s hospitals (CH), but many children still receive care at general hospitals (GH). Little is known about the characteristics of pediatric oncology and HCT patients treated in intensive care units …
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Lifestyle and exercise effects on circulating progenitor cells in children and adults
… proteins and a chronically activated immune system, which is maintained by circulating progenitor cells (CPCs). CPCs are a heterogeneous population of cells that are capable of replenishing the immune system after a hematopoietic stem cell transplant. CPCs reside within the bone marrow niche …
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Hematology-Oncology Transplant Nurses Experience Through the Moral Labyrinth of Integrating Palliative Care
… yet the role of hematology-oncology transplant nurses in facilitating this care remains unclear. This study explored the experiences and understandings of 10 hematology-oncology transplant nurses from across Canada, working in both inpatient and ambulatory settings, regarding the …