Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Hematological malignancy"”.
-
Machine Learning Techniques for Augmenting Hematological Malignancy Diagnosis
… methods to enhance the diagnostic workflow of hematological malignancies, particularly in cytogenetics and clinical flow cytometry. The recent advancements in the field of ML provide a unique opportunity to develop, adapt, and evaluate algorithms for augmenting the hematopathology diagnostic …
-
Pharmacological management of leukemia in children
Leukemia is a hematological malignancy or a cancer of the blood. It develops in the bone marrow. Leukemia is usually described either as "acute" or "chronic". In this thesis, looks into understanding the wide variety of treatment for leukemia in children. in summary, with addition of supportive …
-
NON-GENETIC MECHANISMS OF CHEMORESISTANCE IN ACUTE MYELOID LEUKEMIA
… Leukemia (AML) is the most common type of acute hematological malignancy in adults. 40–60% of patients relapse due to the emergence of cellular resistance to anti- leukemic drugs. Drug resistance in leukemic cells has been associated with intratumoral heterogeneity, among which quiescence, …
-
Multi-Niche Human Bone Marrow On-A-Chip for Studying the Interactions of Adoptive Cell Therapies with Multiple Myeloma
… plasma cells, is the 2nd-most common hematological malignancy. However, despite the advent of immunotherapies like chimeric antigen receptor (CAR) -T cells, which gained FDA approval in March 2021, relapse is nearly universally inevitable. The bone marrow (BM) microenvironment …
-
Critical Illness in Patients with Hematologic Malignancies
Introduction: Patients with hematologic malignancy are at increased risk of developing life-threatening complications that can lead to admission to an Intensive Care Unit (ICU). Acute respiratory failure is the most frequent reason for ICU admission in these patients. Existing knowledge gaps in the …
-
Plasma Extracellular Vessicles, Exercise Resistnace and Cancer
… in EVs isolated from individuals with the hematological malignancy multiple myeloma (MM) and its precursor disease multiple myeloma of undetermined significance (MGUS). This analysis found that CD71 was upregulated in small and large EVs in individuals with MM relative to MGUS, suggesting …
-
Assessing the impact of tumor evolution on oncology drug development and commercialization
… treatment of CML, a relatively rare and indolent hematological malignancy with extensive clinical data available and well-delineated disease phases and response criteria. To represent the rate of diagnosis, patients are "added" to the model every month, and thereafter there is a probability that a …
-
Μελέτη της κλινικής σημασίας της αγγειογένεσης σε ασθενείς με νόσο hodgkin
Angiogenesis has been recently implicated in the pathophysiology and course of various hematologic malignancies. Its significance in Hodgkin’s lymphoma (HL), however, is not known. The purpose of the study was to evaluate various morphometric characteristics of microvessels, highlighted by means …