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Showing 1 to 3 of 3 for “"Helix-sheet"”.
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A multi-level nearest-neighbour algorithm for predicting protein secondary structure
… output a sequence of secondary structures (helix, sheet, or coil). A new training set is developed that is orthogonal, and covers the known classes of proteins. Overall accuracy is 65.0%, with 68.7% accuracy for helices, 66.3% accuracy for sheets, and 61.4% for coils. This compares well with …
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Accurate Docking is Achieved by Decoupling Systematic Sampling from Scoring
… broad melting transition, similar to that of a helix-to-coil transition, was observed in CD, DSC, and REMD experiments. The N-terminal -hairpin was found to be flexible. FSD-1's apparent melting temperature of 41 degrees C may be a reflection of the melting of its alpha-helical segment instead …
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Exploring the molecular architecture of proteins: Method developments in structure prediction and design
<p>Proteins are molecular machines of life in the truest sense. Being the expressors of genotype, proteins have been a focus in structural biology. Since the first characterization and structure determination of protein molecule more than half a century ago1, our understanding of protein structure …