Global ETD Search
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Showing 1 to 3 of 3 for “"Helicobacter pylori infections"”.
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The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori
<p>The rate of successful treatment for Helicobacter pylori infections, with the clarithromycin triple therapy, is only 75%. The triple therapy, which consists of a proton pump inhibitor and two broad-spectrum antibiotics such as clarithromycin and amoxicillin, is becoming less effective due to the …
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A genetic screen to identify novel Helicobacter pylori virulence factors using Saccharomyces cerevisiae as a model eukaryotic cell
<p>"Helicobacter pylori is a spiral, gram-negative bacterium that colonizes the stomachs of approximately 50% of the World's population overall and is a major etiological agent of human gastric adenocarcinoma. Of infected individuals, only 10-15% develop severe gastric disease due to environmental …
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The Recruitment and Function of Tumor Microenvironment Components During Gastric Carcinogenesis
Helicobacter felis (H. felis) infection has been used for numerous years as a standard model of gastric carcinogenesis and recapitulates the pathogenesis seen with human Helicobacter pylori infection. H. felis induces a a wide array of chronic low grade inflammatory responses, some of which …