Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Helicobacter pylori (VacA)"”.
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Helicobacter pylori VacA as a mitochondrial targeted pathogenic effector
… is poorly understood. The vacuolating cytotoxin (VacA) of the human gastric pathogen Helicobacter pylori localizes to and disrupts mitochondrial function. In order to evaluate mitochondrial targeting of VacA, VacA associated cellular compartments were isolated by magnetic based fractionation for …
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Characterization of the Helicobacter pylori vacuolating cytotoxin mediated induction of mitochondrial cell death mechanism
The Helicobacter pylori vacuolating cytotoxin (VacA) is a paradigm for microbial virulence factors that target and disable host cell mitochondria. VacA intoxication triggers mitochondrial dysfunction and metabolic stress, but the mechanisms underlying these perturbations in mitochondrial function …
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Host cellular defense against metabolic alterations induced by Helicobacter pylori vacuolating cytotoxin A
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
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Modulation of host metabolism by the human gastric pathogen Helicobacter pylori
… the host environment for colonization. Helicobacter pylori, a human gastric pathogen that impacts more than a half the human population as the only recognized biological carcinogen, colonizes the highly acidic human gastric environment by modulating host cellular homeostasis. Vacuolating …