Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 148 for “"Helicobacter"”.
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Characterization of metronidazole resistant Helicobacter pylori
The high prevalence of metronidazole resistant Helicobacter pylori (MtzR- Hp ) in relation to gastroduodenal disease is of concern. The study shows that MtzR- Hp is significantly higher in non-ulcer dyspepsia patients ( p = 0.005), expresses lower Le b ( p = 0.0365) and babA2 ( p = 0.03). RAPD …
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Computer-Aided Drug Discovery for Helicobacter pylori
<p>Helicobacter pylori is a high-priority drug-resistant pathogen and is currently the only bacteria considered to be a class I carcinogen and there is a critical need to identify novel chemical matter to treat H. pylori infections. Hp is responsible for greater than 60% of gastric cancer related …
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Untersuchungen zu Adaptationsmechanismen des Magenbakteriums Helicobacter pylori
Das Bakterium Helicobacter pylori persistiert für lange Zeiträume im menschlichen Magen und ist im Rahmen der durch die Infektion induzierten Entzündungsreaktion dauerhaft toxischen Sauerstoffradikalen ausgesetzt, die von Immunzellen, wie neutrophilen Granulozy-ten und Makrophagen generiert werden. …
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Pathogenesis of the carcinogenic bacterium, Helicobacter pylori
… risk factors for gastric cancer, including Helicobacter pylori infection, low fruit and vegetable intake, N-nitrosoamine exposure, high salt diet, and smoking. Among these risk factors, H. pylori infection is the major cause of gastric cancer. Therefore, H. pylori has been classified as a …
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An exploratory study of Helicobacter suis control strategies
Helicobacter suis is a Gram-negative, spiral-shaped bacterium that colonizes the stomach of the majority of slaughter pigs worldwide. An infection with this microorganism has been associated with erosive and ulcerative lesions in the non-glandular part of the porcine stomach and with chronic …
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Molecular pathogenesis of Helicobacter hepaticus induced liver disease
Helicobacter hepaticus infection of A/JCr mice is a model of liver cancer resulting from chronic active inflammation. We monitored hepatic global gene expression profiles and correlated them to histological liver lesions in H. hepaticus infected and control male A/JCr mice at 3 months, 6 months, …
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Immunomodulation by subclinical persistent infection with Helicobacter hepaticus
… or inflammatory bowel disease. Infection with Helicobacter hepaticus is subclinical and persistent in C57BL/6 mice, but causes disease in susceptible strains and immunodeficient mice. To test the hypothesis that subclinical persistent infection modulates the host response to diarrheal disease a …
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Advanced Clinical, Diagnostic and Therapeutic Aspects of Helicobacter Pylori Infection // Съвременни клинико-диагностични и терапевтични аспекти на инфекцията с Helicobacter pylori
… труд е посветен на актуална тема: инфекцията с Helicobacter pylori, която е най- честата инфекция при човека. Масово е разпространена и засяга 50 от човечеството и е причина за развитие на острия и хроничния гастрит, атрофичния гастрит, стомашна язва, дуоденална язва, MALT лимфом и стомашен рак. …
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Untersuchungen zur Regulation Motilitäts-assoziierter Gene in Helicobacter pylori
Helicobacter pylori ist ein an seine ökologische Nische hochgradig angepasstes Bakterium, das den Magen von mehr als 50% der Weltbevölkerung chronisch besiedelt. Bei 10 bis 20% der Infizierten können schwerere Krankheitsverläufe von Magengeschwüren bis hin zu Karzinomen auftreten. Die …
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Identifikation von in vivo essentiellen Genen bei Helicobacter pylori
… tagged mutagenesis (STM) wurden Gene bei Helicobacter pylori identifiziert, die für die das Überleben von Helicobacter pylori im Magen von Mongolischen Wüstenrennmäusen essentiell sind.
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Helicobacter pylori gene regulation by virulence region located sRNAs
… 50% of the human population is infected with Helicobacter pylori, which can lead to gastrointestinal diseases such as ulcers and gastric adenocarcinoma. Helicobacter pylori strains are genetically variable, and some contain a DNA region called the cytotoxin associated gene pathogenicity island …
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Characterization of Helicobacter pylori sRNAs HPnc2525, HPnc2600, and HPnc2645
<p>Helicobacter pylori is a common microaerophilic gram-negative bacterium that infects approximately 50% of the human population. Although all H. pylori infections result in inflammation of the gastric epithelium, only 10-15% of infections are symptomatic and progress to severe gastric diseases …
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Helicobacter pylori VacA as a mitochondrial targeted pathogenic effector
… cytotoxin (VacA) of the human gastric pathogen Helicobacter pylori localizes to and disrupts mitochondrial function. In order to evaluate mitochondrial targeting of VacA, VacA associated cellular compartments were isolated by magnetic based fractionation for proteomic analysis. Several proteins …
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The transcriptional control of virulence gene expression in Helicobacter pylori
… spiral-shaped, microaerophilic bacterium Helicobacter pylori is the causative agent of various disorders of the upper gastrointestinal tract, such as chronic superficial gastritis, chronic active gastritis, peptic ulceration and adenocarcinoma. Although many of the bacterial factors …
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Epidemiología, diagnóstico molecular y estudio de resistencias de Helicobacter pylori
La infección por Helicobacter pylori es una de las más prevalentes a nivel mundial, y se relaciona principalmente con patología digestiva. Su incidencia tiende a disminuir en los últimos años en los países occidentales, aunque el incremento de las resistencias a los antimicrobianos comienza a …
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Helicobacter pylori and its Association with Gastric and Oesophageal Carcinomas
Helicobacter pylori is one of the most common infections in man. The infection is often acquired during childhood and usually results in a chronic life-long inflammation in the gastric mucosa. The aim of our studies was to investigate the association between H. pylori seropositivity and the …
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