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Showing 1 to 20 of 438 for “"Heat shock"”.
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Protection of Artemia from vibriosis by heat shock and heat shock proteins
… losses. During my work the application of heat shock proteins (Hsps) as an approach to disease control in aquaculture was explored, with gnotobiotic brine shrimp Artemia larvae as the model organism. The thesis contains several findings, featuring the interesting observation that a …
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Polymorphisms in heat shock protein receptors
Das extrazelluläre Hitzeschockprotein 70 (Heat Shock Protein 70, HSP70) kann als immunologisches Gefahrensignal fungieren und stimuliert die Aktivität zytotoxischer T-Lymphozyten und natürlicher Killerzellen. In diesem Kontext stellt HSP70 ein vielversprechendes Werkzeug im Rahmen immunologischer …
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Heat shock proteins as immunological carriers
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.
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Effects of heat shock, hypoxia, post-mortem interval and glioma disease state on heat shock gene HSPA expression
Heat shock protein 70 (HSPA/HSP70) gene expression is induced by a wide range of cellular stress conditions. This study investigated HSPA/HSP70 expression in human cell lines exposed to hypoxic conditions, in cancerous and non-cancerous brain tissue specimens from 18 patients (gliomas and normal …
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Heat shock proteins in Mojave Desert dragonflies
Temperature plays a crucial role in the constant interaction between organisms and the environment. It affects development and rates of physiological functions as well as survival of organisms.
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Heat shock proteins in Mojave Desert dragonflies
Temperature plays a crucial role in the constant interaction between organisms and the environment. It affects development and rates of physiological functions as well as survival of organisms.
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Heat shock proteins as indicators of environmental stress
In order to determine whether heat shock proteins (HSP) can be used as indicators of environmental stress in the mammalian organism Peromyscus leucopus, three doses of each of two chemical stresses, cadmium chloride and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), were given intraperitoneally for …
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Kinetics study of heat shock protein 70 expression
Heat shock protein 70 (HSP70) is well known for its efficacy in cardiac ischemia protection. The purpose of this study was to determine HSP70 expression kinetics in response to mild thermal stress. Currently there are no comprehensive experimental HSP70 expression kinetics data available. An …
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Structural and Functional Evolution of Human Heat Shock Transcription Factors
… cellular stress response is the activation of Heat Shock Transcription Factors (HSFs) that regulate the expression of numerous genes involved in protein folding, protein degradation, and cellular survival. The studies presented here utilize a diverse array of techniques including yeast …
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Aedes aegypti Heat Shock 70 Genes and their Inducible Promoters
… in this mosquito. The Drosophila melanogaster heat shock 70 promoter has been shown to drive inducible expression in heterologous systems; however, DmHsp70 possesses significant basal activity in Aedes aegypti. This study characterized the sequence and expression of the heat shock 70 genes of …
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Development And Study Of Inhibitors Of Heat Shock Protein 70 Induction
Tumor and cancer cells that over express heat shock protein 70: HSP70) are found to be multidrug resistant and thermo tolerant, creating a hurdle to existing therapy. Although HSP70 is recognized as an increasingly important drug target, the protein structure of this highly conserved chaperone …
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Discovery of heat shock protein90 inhibitors using structured-based virtual screening
… the illness, but rather as symptomatic therapy. Heat Shock Protein (HSP90), is one of the molecular chaperones that plays a role in AD pathogenesis. HSP90’s main function is to regulate the heat shock factor-1 (HSF-1) transcription factor, which is the key regulator of the heat shock response. …
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Are thermotolerance and heat acclimation related through the heat shock response?
… that allow survival after an acute, severe heat exposure) and heat acclimation (systemic adaptations that improve heat dissipation following chronic heat exposure) have traditionally been considered separate phenomena. However, recent studies in animals suggest these adaptations may be …
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The Gordian knot of small heat shock proteins and tissue transglutaminae
Contains fulltext : 32056_gordknofs.pdf (Publisher’s version ) (Open Access) Contains fulltext : 72514.pdf (Publisher’s version ) (Open Access)
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Characterization of Heat Shock Protein A12B as a Novel Angiogenesis Regulator.
<p>Previously, we cloned Heat shock protein A12B (HspA12B), the newest member of a recently defined subfamily of proteins distantly related to the Hsp70 family that are enriched in atherosclerotic lesions. We have found that HspA12B is predominantly expressed in vascular endothelium, and that it is …
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The Arabidopsis thaliana Heat Shock Transcription Factor A1b Transcriptional Regulatory Network
… complex transcriptional regulatory circuits. The heat shock transcription factors (HSFs) have been shown to be central regulators of plant responses to abiotic and biotic stress conditions. However, the extremely high multiplicity in plant HSF families compared to those of other kingdoms and their …
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Stress Conditioning and Heat Shock Protein Manipulation for Bone Tissue Engineering
External stresses surrounding bone can stimulate heat shock proteins (HSPs), which are involved in anti-apoptosis, cell proliferation, and differentiation. In vitro stress modulation and HSP induction may be critical factors for enhancing bone regeneration. We investigated whether applying …
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Characterization of PFF1010c, a type IV Plasmodium fasciparum heat shock protein 40
… its molecular chaperones machinery particularly heat shock proteins (Hsps) to protect its protein constituents during physiological stress. Hsps are conserved molecules that constitute a major part of the cell’s molecular chaperone system. P. falciparum Hsps play an important cyto-protective role …
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Heat shock protein 27 inhibition of apoptosis in human breast cancer cells
Cancer occurs when normal cells fail to die in response to various cell death signals. Normal eukaryotic cells exhibit two major forms of cell death--Necrosis and Apoptosis. Apoptosis can be triggered in cells by various agents. Studies have shown that an elevated amount of Hsp 27 protects cells …
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