Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Heartworm"”.
-
The identification of novel cys-loop receptor genes in Dirofilaria immitis
… is a parasitic nematode responsible for canine heartworm disease. Currently, heartworm treatments rely primarily on a single drug class – the macrocyclic lactones – but anthelmintic resistance is emerging. Cys-loop ligand-gated ion channels are an untapped source for drug targets essential for …
-
Identification and characterization novel of cystine-loop ligand- gated chloride channels from Dirofilaria immitis: pharmacological analysis and novel compound screening
Dirofilaria immitis, otherwise known as heartworm, is a parasite that infects the hearts of dogs and causes serious health consequences. While preventative treatments are available drug resistance is developing at an alarming rate. Cystine-loop ligand-gated ion channels are important receptors in …
-
La Crosse virus and Dirofilaria immitis: Abundance of Potential Vectors in Southwestern Virginia and the Effects of Dual Infection on Aedes albopictus and Ochlerotatus triseriatus
… immitis, the nematode that cause canine heartworm disease. Ae. albopictus and Oc. triseriatus are important vectors of La Crosse virus and among the numerous species able to transmit D. immitis. In this study, Aedes albopictus and Ochlerotatus triseriatus were infected with La Crosse …
-
Investigation into potential Dirofilaria immitis drug targets through rational anthelmintic synthesis and design
Dirofilaria immitis is a mosquito-transmitted parasitic nematode that can cause debilitating disease in dogs. D. immitis is present in Canada and over the years has increased in prevalence due to several factors including climate change. Anthelmintic resistance is becoming increasingly problematic …