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Showing 1 to 8 of 8 for “"Heart--Physiology"”.
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mIGF-1 regulates heart physiology and induces complete regeneration of infarcted myocardial tissue
ABSTRACT The mammalian heart is particularly susceptible to traumatic injury or sustained disease, suffering tissue deterioration, scarring and loss of contractile function. Clinical interventions to prevent or reverse the devastating effects of cardiac damage have met with limited success, …
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The Effect of Exercise Training on the Response of Isolated Rat Atria to Acetylcholine at 30°C and 37°C
The effect of exercise on heart physiology was investigated on thirty-six male Sprague-Dawley rats. Twenty-four were subjected to a daily treadmill exercise program over a fourteen week period. Body weights, and resting heart rates were measured in the intact rats. Atria were isolated in an organ …
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Myocardial Contractility in Fetal Sheep Exposed to Long-term Hypoxia at High Altitude : Activator Calcium and Beta-adrenergic Receptor Function
<p>We studied myocardial contractility in fetal sheep exposed to ~112 days of hypoxia at high-altitude (3,820 m). We recorded left and right ventricular wet weight, and measured the inotropic responses to extracellular calcium [Ca<sup>2+</sup>]<sub>o</sub> (0.2-10 mM), ryanodine …
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Basal Release of Endothelium-derived Nitric Oxide in Thyropathologic Rat Aorta
Systolic blood pressures, basal metabolic rates, and circulating catecholamine levels were determined for hyperthyroid (TRX), hypothyroid (PTU), and euthyroid control (CON) rats. All three measurements were elevated in TXX animals, while PTU rats were determined to have decreased measurements when …
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Cardioregulatory Role of the Abdominal Ganglion of APLYSIA CALIFORNICA
<p>An isolated heart-abdominal ganglion preparation of this mollusc was developed and used to study the cardioregulatory function of the ganglion and nerves. The heart was perfused with artificial sea water through an atrial cannula and the gastro-esophageal artery was catheterized for blood …
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Molecular Mechanisms That Govern Human Cardiac Stem Cell Age Disparity
… endogenous cardiovascular progenitor cells for heart repair results in some clinical benefit, however these stem cells lack the regenerative capacity unique to neonatal cardiovascular stem cells. The goal of this work was to identify mechanisms that contribute to the decline of cardiac stem cell …