Global ETD Search
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Showing 1 to 17 of 17 for “"Heart rhythm"”.
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Uncertainty in the Bifurcation Diagram of a Model of Heart Rhythm Dynamics
… the underlying mechanisms of cardiac arrhythmias, computational models are used to study heart rhythm dynamics. The parameters of these models carry inherent uncertainty. Therefore, to interpret the results of these models, uncertainty quantification (UQ) and sensitivity analysis (SA) …
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AMPK-MEDIATED LONG-TERM REGULATION OF HCN4CONTRIBUTES TO AGE-RELATED SINUS BRADYCARDIA
… inward depolarizing currents, called If in the heart and Ih in the brain, that contribute to the regulation of neuronal excitability and cardiac rhythm. Among the HCN isotypes, HCN4 stands out for its prominent role in pacemaker activity in the heart where it acts as a key element for the heart …
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From Ecological Epitome to Medical Model: An investigation into Applications for the use of Daphnia in Heart Science.
… more accurate and efficient means of gathering heart rhythm data by recording heart movement from whole live Daphnia. This opens the way to individualising cardio therapeutics; by correlating the stability of individual hearts with response to cardiac insult, regression analysis provides a means …
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An exploration of the molecular mechanisms underlying the effects of hyperglycaemia on the autorrhythmicity of cardiac-like stem cells
… hyperglycaemia is a major risk factor for heart rhythm disturbances. Hyperglycaemia during pregnancy is particularly concerning, as offspring of poorly controlled diabetic mothers are at an increased risk of developing life-long serious cardiovascular complications. Although structural …
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Radiofrequency ablation versus cryoablation in the treatment of atrioventricular nodal reentrant tachycardia
… reentrant tachycardia (AVNRT) is an abnormal heart rhythm caused by aberrant electrical conduction within the AV node. AVNRT is the most common type of paroxysmal supraventricular tachycardia (PSVT), with approximately 50,000 new cases per year in the United States. Catheter ablation of AV …
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Measurement of Radiofrequency Induced Heating in Patients with Retained Post-Surgical Epicardial Leads During MRI
In the 2017 Heart Rhythm Society consensus statements, scanning of nonconditional cardiac implantable electronic devices in the presence of epicardial leads were classified as contraindications in MRI. Much of the concerns were due to the possibility for the lead to interact with the radiofrequency …
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St. Jude Medical: Enhanced MICS (eMICS)
Heart disease is one of the most prevalent diseases in the world. The survival chances for patients with ventricular fibrillation/ventricular tachycardia reduces significantly as time passes without treatment and even after getting timely treatment recurring episode are common. These patients can …
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Novel Formal Methods for the Safety and Security of Cyber-Physical Systems
… a smart watch alerting if it detects abnormal heart rhythm. For CPSs with the ability to take action, runtime enforcement is well suited to ensure safety and security policies are upheld. Runtime enforcement extends runtime verification with the ability to intervene before a violation occurs …
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Electrocardiographic Findings During Standard Hands Only CPR and Hands Only CPR Plus Pedal CPR in Senior Rescuers
<p>The standard first aid for a heart attack resulting in cardiopulmonary arrest is effective cardiopulmonary resuscitation (CPR). Chest compressions are most commonly performed on a flat surface with the rescuer kneeling next to the victim with one hand on top of the other on the sternum and …
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Source characterization using linear transformations of multichannel biomagnetic recordings
… the brain, via magnetoencephalography (MEG), and heart, via magnetocardiography (MCG). Dense-array biomagnetometers have been recently designed for the investigation of the neurophysiological development of the fetus in utero. Fetal MCG offers accurate recordings of the fetal cardiac activity that …
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Design, Fabrication and Modelling of Intracardiac Catheter for Electrical Mapping of Atrial Fibrillation
Atrial Fibrillation (AF) is the most common heart rhythm disturbance affecting one quarter of people older than 40 years old. It is predicted to affect 6 – 12 M people in the USA by 2050 and 17.9 M in Europe by 2060 (Schnabel et al. 2015). Catheter ablation is a treatment for patients with …
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Arrhythmias in Pulmonary Hypertension
Cardiac arrhythmias are common in patients with pulmonary arterial hypertension (PAH) due to structural and electrical remodelling of the right heart, and are associated with adverse clinical outcomes. This study investigated the prevalence and clinical significance of conduction abnormalities and …
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Central autonomic control in spontaneously hypertensive rats: a study on phasic phenomena during rapid-eye-movement sleep
… relationship between spontaneous fluctuations in heart period and arterial pressure clearly shows differences between the two sleep states. In non rapid-eye-movement sleep, heart rhythm is under prevalent baroreflex control, whereas in rapid-eye-movement sleep central autonomic commands prevail …
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A Comprehensive Evaluation of Cardiac Electro-Anatomic Mapping Using Body Surface Potentials
… can provide clinically useful information about heart rhythm disturbances. To date, a complete in-vivo validation of this inverse mapping approach has not been performed in large animals or humans. The principal objectives of this thesis were to evaluate the accuracy and reliability of inverse …
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Assessment of Cardiac Function by Acoustic Radiation Force (ARF) Based Methods of Ultrasound Elastography
<p>Heart Failure (HF) is a major cause of morbidity and mortality in the world. This disorder is characterized by compromised systolic and/or diastolic function of the myocardium that reduces the pumping and/or filling efficiency resulting in diminished cardiac output. Cardiovascular researchers …
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ZEBRAFISH (DANIO RERIO) AS A MODEL SYSTEM FOR THE FUNCTIONALVALIDATION OF CANDIDATE GENES FOR HUMAN DISEASES
… syndrome (TKOS). TKOS is a rare, inherited arrhythmogenic cardiac disorder, possibly leading to exercise-induced cardiac arrest in early childhood. Homozygous mutations in the triadin (TRDN) gene, encoding for a 7 muscular protein essential for the structural integrity of the calcium release …