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Showing 1 to 5 of 5 for “"Heart -- Metabolism"”.

  1. Mitochondrial protein acetylation and left ventricular function in a model of hypertrophic cardiomyopathy and heart failure

    Stram, Amanda R.2017

    Rationale: The childhood heart disease of Friedreich’s Ataxia (FRDA) is characterized by hypertrophy and failure. It is caused by loss of frataxin (FXN), a mitochondrial protein involved in energy homeostasis. FRDA model hearts have increased mitochondrial protein acetylation and impaired sirtuin 3 …

    iupui Repository record

  2. Catecholamine Interactions with the Cardiac Ryanodine Receptor

    Klipp, Robert Carl

    portland-state Repository record

  3. Mitochondrial Reactive Oxygen Species (ROS): Which ROS is Responsible for Cardioprotective Signaling?

    Garlid, Anders Olav

    portland-state Repository record

  4. Regulation of Protein Degradation In The Heart By Amp-Activated Protein Kinase

    Baskin, Kedryn K2012

    … is essential for cellular homeostasis in the heart. An important regulator of metabolic homeostasis is AMP-activated protein kinase (AMPK). During nutrient deprivation, AMPK is activated and intracellular proteolysis is enhanced through the ubiquitin proteasome system (UPS). Whether AMPK plays …

    uthsc Repository record

  5. CARDIAC ENERGY METABOLISM IN ISCHAEMIA AND TYPE 1 DIABETES

    Lindsay, RossUniversity of Cambridge2019

    Ischaemic heart disease represents a restriction of blood, and therefore oxygen, supply to the myocardium. This leads to a remodelling of cardiac metabolism, which can exacerbate production of damaging reactive oxygen species and tissue necrosis upon reperfusion. In a different paradigm of …

    cambridge Repository record