Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 362 for “"Health and Disease"”.
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Biopterin metabolism in health and disease
… Secondly the urine concentration of neopterin and biopterin was estimated by high performance liquid chromatography. Thirdly the urine concentration of tetrahydrobiopterin was determined by an enzymatic assay using phenylalanine hydroxylase. The results obtained have been correlated with …
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Platelet kinetics in health and disease
[Typescript]
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Prion protein in health and disease
… many tissues, most abundantly in brain, heart, and muscle. Importantly, PrP is required for prion diseases, which are neurodegenerative diseases associated with misfolding and aggregation of PrP. PrP can adopt a self-perpetuating conformation that templates the misfolding of normal PrP molecules …
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Procollagen Folding in Health and Disease
Procollagen is a large, complex, and in many ways, unusual protein that is ubiquitous in the human body and in all animals. Decades of research have advanced our understanding of how cells fold and secrete this protein, nonetheless, many questions remain concerning procollagen biosynthesis, and how …
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Polyclonal somatic mutations in health and disease
[Restricted]
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Mitochondrial Structure-Function in health and disease
Mitochondrial structure and function are inextricably linked ("structure-function"), with decrements in structure-function evident across diseases. Barriers to new therapies include a complete understanding of the underlying molecular culprits, as well as effective mitochondria-targeted therapies …
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Trafficking of aquaporin-2 in health and disease
Contains fulltext : mmubn000001_345930894.pdf (Publisher’s version ) (Open Access)
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Defining gut mediated metabolism for health and disease
… the overall concept that human produced and microbially modified bile acids could act as an indicator of health. In chapter 3 we verified disruptions to bile acid metabolism in a porcine model of metabolic syndrome towards cardiovascular disease, induced by diet. In chapter 4 we applied …
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Plasma and leukocyte gelatinases in health and disease
Includes bibliographical references.
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Exercise and peripheral vascular function in health and disease
“Chronic disease will never reach its clinical horizon to compromise health if it is attacked at its origin” [1]. Knowledge that one’s risk for cardiovascular events is related to the severity of endothelial dysfunction, and evidence that exercise training can improve endothelial function, has …
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Modern concepts of the platelet in health and disease
Thesis (M.D.)--Boston University
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Migration of human tympanic epithelium in health and disease
… middle ear space produces a proliferating, expanding mass which cannot escape from its enclosed environment. This condition, described as <i>cholesteatoma*</i>, can, in turn, invade the facial nerve, inner ear and intracranial contents and require surgical intervention which in itself poses …
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The application of metabolomics in human health and disease
… growing tools for the identification of new disease diagnostic biomarkers. Mass spectrometry (MS) coupled to a liquid chromatographic (LC) system and nuclear magnetic resonance (NMR) are the two major analytical plaforms currently employed in metabolomic profiling studies of complex biofluid …
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Exercise and Oxidative Stress: Implications in Health and Disease
… Electron Spin Resonance (ESR) spectroscopy and the by-products of lipid peroxidation.<br/><br/>It has been proposed that exercising in hypoxia may increase free radical production. Thus study one investigated the effects of aerobic exercise performed in normobaric hypoxia …
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Structure and function of aquaporins in health and disease
Contains fulltext : mmubn000001_250374951.pdf (Publisher’s version ) (Open Access)
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Study of the heart muscle in health and disease
… to examine all heart conditions from the standpoint of the heart muscle and it aims at emphasising the great importance of the myocardium in cardiac disease. Modern research has shown conclusively that whatever kind of heart-lesion may be present, the real factor of importance is the state …
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Investigation of Microbiota in Health and Disease of Poultry
<p>The microbiotas play vital roles in health and diseases of both humans and animals. 16S rRNA genes sequence analysis is one of the most popular and commonly used methods in the analysis of microbiotas associated with hosts. In this dissertation, the microbiotas of chickens (broilers, breeders, …
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Cellular Kaleidoscope: Unveiling Tissue Microenvironment in Health and Disease
… work together to perform specific tasks. Understanding how tissues and organs function requires insight into the dynamics between different cell populations. Changes in this composition and gene expression patterns within a tissue can indicate a disease manifestation. Single-cell RNA sequencing …
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Morphogenetic Principles of Brain Organisation in Health and Disease
… This thesis provides novel analyses, pipelines and methods to: i) generate and validate maps of brain organisation obtained via MRI, and ii) demonstrate the utility of these methods in capturing elements of cognition and psychopathology. First, in Chapter 1, I review some of the neuroscientific …
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