Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Haptotaxis"”.
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Integrin alpha(v) and Focal adhesion kinase - promising targets to limit smooth muscle cell migration
… Inhibition der durch VN stimulierten Migration (Haptotaxis) mit Hilfe des V Inhibitors korrelierte mit der Reduktion der Aktivierung Integrin vermittelter Signalwege, im Besonderen der PTyr von FAK. Interessanterweise konnte die Blockade von Integrin V nicht nur die durch VN stimulierte …
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Mathematical Modelling of Cancer Growth and Spread: The Role of Matrix Metalloproteinases
… model of cancer cell invasion primarily through haptotaxis as the result of degradation of tissue from the proteolytic activity of the membrane bound MT1-MMP protein and the soluble MMP-2 protein in addition to the complexes formed, and consequences thereof, from interactions they have with one …
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Manipulating soft materials to direct cell growth in multiple dimensions
… processes, examples of which include chemotaxis, haptotaxis, axonal guidance and angiogenesis, has been a relevant research focus for many years. Microfabrication techniques involving soft lithography, microfluidic devices and direct-write assembly can be used to create such microenvironments. …
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Modeling cell proliferation in a perfusion tissue engineering bioreactor
… and enhance proliferation via a process known as haptotaxis. While a quantitative representation of these phenomena requires more experimental data than are yet available, qualitative agreement with preliminary experimental studies is obtained, and appears promising. The ultimate goal of such …
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Netrin Guides Spinal Commissural Axons to the Midline at Long Range Through the Receptors Dcc and Neogenin
… in solution (chemotaxis) or bound to surfaces (haptotaxis). A gradient of Netrin-1 along the dorsal-ventral axis of the spinal cord is thought to attract commissural axons to the midline, with the floor plate being a major source of diffusible Netrin. However, this view has recently been …
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Multiscale Modelling of Cancer Response to Viral Therapy
… over the tumour - OV interaction, in the form of haptotaxis of both uninfected and infected cells populations as well as the indirect ECM taxis for the oncolytic virus. The complex tumour-OV interactions are also investigated numerically through the development a new multiscale moving boundary …
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A Novel Biomaterial Enables Chemotactic Study of Motile Central Nervous System-derived Tumor Cells
… MB chemotactic study towards EGF with minimal haptotaxis, i.e. migration induced along the ECM alone .CMC gels used as ECM thereby facilitate unique, mechanistic study of MB chemotaxis because the hydrogel itself minimizes integrin interactions between cells and the ECM. This phenomenon was …
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Cell Migration on Opposing Rigidity Protein Gradients: Single Cell and Co-culture Studies
Cell migration is a complex physiological process that is important from embryogenesis to senescence. In vivo, the migration of cells is guided by a complex combination of signals and cues. Directed migration is typically observed when one of these cues is presented to cells as a gradient. Several …
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Molecular Mechanism of Tetraspanin CD9 Mediated Cell Motility
<p>CD9, a member of the tetraspanin superfamily of proteins participates in the regulation of cell adhesive functions such as cell migration. The mechanisms underlying CD9 mediated cell migration are not known. In the current study, we investigated the molecular basis for the CD9 promoted cell …