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Showing 1 to 3 of 3 for “"Halofuginone"”.
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Metabolism of halofuginone in rats and sheep fed excreta from poultry administered halofuginone orally
The fate of halofuginone and its metabolites from poultry when they were refed to rats was investigated. During a 6 d accumulation period rats excreted .607 uCi or 53.8% of the administered dose in the feces. The urinary output accounted for .157 uCi or 13.7% of intake. The rats respired 1.5% of …
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Extracellular-matrix mediated regulation of human uterine leiomyoma smooth muscle cells and potential targeting by the anti-fibrotic drug halofuginone
… inhibitory effects of the anti-fibrotic drug, halofuginone (HF), on the growth of leiomyoma tumors in both in vitro and in vivo model systems. Our research in understanding the pathogenesis of leiomyomas showed that (1) monomeric and fibrillar forms of ECM collagen can differentially regulate …
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Dual-Chambered Membrane Bioreactor for the Dynamic Co-Culture of Dermal Stratified Tissues
… the keratin bioink in the production of Halofuginone-laden face masks for the improvement of contracture, scarring, and aesthetics in severe skin wound healing in an animal model. Due to lack of collagen organization and microstructural development, we introduced a novel dual-chambered …