Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 653 for “"Hallmark"”.
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Bring All People Together: Maximizing Diversity & Inclusion at Hallmark Cards, Inc.
… on diversity to one of inclusion, how can Hallmark use this shift as an opportunity to create a more emotionally connected world?
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A Statewide Hallmark Event: The Exploration of Participants' Perceptions and Emotions
… and perceptions of participants in a state-wide Hallmark event. To achieve the purpose of this study, this research studied the perception and emotions of the participants of the state-wide event. Participants filled out an online survey with questions related to their sense of community, …
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Global alterations of the epigenetic landscape define endometrial receptivity and provide a hallmark for endometriosis
The endometrium plays an essential role in the female reproductive cycle. It undergoes extensive morphological and transcriptional changes during the menstrual cycle, in response to steroid hormones. For implantation to occur successfully, the endometrium must attain a receptive state which is …
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Knowledge-based expertise as the hallmark of work of risk : an analysis of the curriculum and pedagogy of a National Diploma in Train-Driving
This study examines the suitability of competency-based modular education and training as preparation for skilled vocational work. In particular, it explores the nature of the curriculum and pedagogy that leads to the transmission and acquisition of risk work; defined as work that involves inherent …
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Towards an integrated understanding of low-dose chemical exposures in the development of human cancer
… of twelve teams was organized to review 11 hallmark phenotypes of cancer and identify priority target sites for disruption in each area. Prototypical chemical disruptors for all targets were then identified, and dose-response information was gathered. Evidence of low-dose effects for each …
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Elucidating the molecular basis of a novel autosomal dominant fibrotic syndrome
… progressive pulmonary fibrosis. The pathological hallmark of this autosomal dominant condition is abnormal fibrosis of the skin, tendons and viscera, with variable penetrance. A candidate gene approach was adopted to investigate the molecular basis of this disease.
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Model-based control of spatially extended systems
… the realm of partial differential equations. The hallmark of model-based control is that a particular goal dynamics is achieved by using a model for the observed dynamics to create the appropriate driving needed to make the goal dynamics an attractor for the system, alleviating the need for …
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STAUROSPORINE-INDUCED APOPTOSIS/PROGRAMMED CELL DEATH
… al., 1996; Swe and Sit, 1997). The biochemical hallmark of apoptosis has for a long time been held as the manifestation of 200 bp DNA ladder cleavages. It is now clear that this DNA ladder hallmark is a late stage event in the third or degradation phase of apoptosis. Upstream kilobase level …
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The Assessment and Treatment of Conversational Skills for Individuals with Autism Spectrum Disorder: A Replication and Extension
Deficits in social skills are considered a hallmark of autism spectrum disorder (ASD) and have been shown to impact quality of life, but the research on effective social skills interventions for the adolescent population is lacking. Specifically, more research is needed on complex social skills, …
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Geroprotective and antineoplastic functions of protein homeostasis
… tal que se ha identificado como uno de los nueve hallmarks del envejecimiento, así como un hallmark de la salud. En la presente Tesis Doctoral, hemos explorado las funciones geroprotectoras y antineoplásicas de la homeostasis proteica mediante la generación de dos nuevos modelos animales.
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Advancing Health and non-Health Security, Diplomacy and International Relations through the Enlightened Design and Delivery of Smart Global Health Programs
… such cases, such enlightened approaches are the hallmark of enlightened human evolution.
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Identifying the Molecular Cause of Extreme Endoplasmic Reticulum Dilation in Pediatric Osteosarcoma and Its Relationship to the Disease
… accumulation of procollagen-I protein within ‘hallmark’ dilated ER. Using CRISPR activation technology, increased expression of only SAR1A and SEC24D to physiologically normal levels was sufficient to restore both collagen-I secretion and resolve dilated ER morphology to normal. </p>
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Molecular origins of tissue vulnerability to aberrant aggregation in protein misfolding diseases
… β (Aβ) and tau in AD and α-synuclein in PD, hallmark these disorders, such behaviour is a consequence of a wider, system-level disruption of protein homeostasis. In order to identify the genetic factors contributing to such a disruption, the transcriptional changes that occur during …
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Semantic text classification for cancer text mining
… of semantic text classification according to the Hallmarks of Cancer (HoC), which enables text mining of scientific literature assisted by a taxonomy that explains the processes by which cancer starts and spreads in the body. The second task is that of the exposure routes of chemicals into the …
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The Role of Bps Polysaccharide in Bordetella Resistance to Host Innate Defenses
… the effectiveness of host responses. A hallmark of mature biofilms is the production of a matrix composed of extracellular polymers including proteins, DNA and polysaccharides. We have shown that the <italic>bps</italic> locus is required for biofilm formation and production of the …
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Ultracold fermionic atoms in disordered potentials
… the first measurement of how the mobility edge—a hallmark of 3-dimensionality—and of localization lengths depend on the disorder strength. In a second experimental study, we add an optical lattice to the disorder potential to realize the disordered Fermi-Hubbard model, which is a minimal model for …
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Pathobiology of neuroinflammation and basal ganglia circuitry in Parkinson’s Disease
… termed the substantia nigra (SN). Another hallmark feature of PD pathology is the presence of Lewy bodies and Lewy neurites, which are cellular inclusions with aggregated protein depositions, representing pathology in neuronal cell bodies and neuritic processes. Recently, epidemiological …
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Teaching Gospel-Oriented Ecclesiology to Members of Ichthus Mission Church in Rockville, Maryland
… to show that congregational unity is a central hallmark of the New Testament vision for the church. Chapter 3 presents theological, practical, and historical issues related with the unique dynamics of ethnic churches. Chapter 4 describes the project itself, recounting the content and teaching …
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Defining the role of 4-hydroxy-2-oxoglutarate aldolase in hydroxyproline metabolism and primary hyperoxaluria
Aberrant glyoxylate metabolism is a hallmark of primary hyperoxaluria (PH). PH types 1 and 2 are the consequence of functional defects in alanine-glyoxylate aminotransferase (AGT) and glyoxylate reductase (GR), respectively. The resulting increase in oxalate excretion can lead to the formation of …
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Southern Post-Modernism, Anti-Romanticism and Gender Difference in Flannery O'Connor and Some Other Southern Contemporaries
… at how O'Connor's fiction makes her a key hallmark figure in the movement known as Post-Modernism, but also as one of the first female southern writers to utilize very anti-Romantic themes and style. Further, this paper attempts to examine through a discussion of various contemporary male …
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