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Showing 1 to 2 of 2 for “"Hair Follicle Bulge"”.
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Transcriptional functions of the corepressor Sin3A in skin
… models. To determine whether Sin3A functions in hair follicle stem cells, I inducibly deleted Sin3A in the hair follicle bulge, where quiescent stem cells reside. However, lack of Sin3A in the hair bulge did not cause any aberrant phenotype and I concluded that Sin3A is dispensable for hair …
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Role of Stat3 In Keratinocyte Stem Cells During Skin Tumorigenesis
… (KSCs). Deletion of Stat3 specifically in the bulge region of the hair follicle using K15.CrePR1 X Stat3<sup>fl/fl </sup>mice led to decreased tumor development by altering survival of bulge region KSCs. To further understand the role of KSCs in skin tumorigenesis, K5.Stat3C transgenic (Tg) …