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Showing 1 to 2 of 2 for “"Hair Disease"”.

  1. The Role of Insig-Mediated Cholesterol Homeostasis in Mouse Hair Development

    … a line of mice lacking both Insigs in the hair and skin. These epidermal-specific, Insig-double knockout mice have many skin abnormalities, but their most striking defect is a complete lack of body hair. Epidermal-specific, Insig-double knockout mice also have a significant buildup of …

    utswmed Repository record for The Role of Insig-Mediated Cholesterol Homeostasis in Mouse Hair Development (opens in a new tab)

  2. Role of Insig-Mediated Cholesterol Homeostasis in the Development of the Palate and Hair Follicles in Mice

    … and cardiovascular anomalies. In each of these diseases, there is a block at a specific enzymatic step leading to a deficiency in cholesterol and a concomitant buildup in sterol intermediates proximal to the block; however, it is unclear whether cholesterol deficiency or sterol intermediate …

    utswmed Repository record for Role of Insig-Mediated Cholesterol Homeostasis in the Development of the Palate and Hair Follicles in Mice (opens in a new tab)