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Showing 1 to 20 of 57 for “"Haemophilus influenzae"”.

  1. Haemophilus influenzae as a chassis for directed endosymbiosis

    Hamadache, SamirThe University of Western Ontario2026

    … between distinct species. This thesis explores Haemophilus influenzae as a candidate chassis for directed endosymbiosis with Saccharomyces cerevisiae. H. influenzae is small, genetically tractable, naturally competent for DNA uptake, facultatively intracellular, and dependent on host-relevant …

    uwo Repository record

  2. Haemophilus influenzae adhesins and the innate immune response

    Ronander, ElenaMedical Microbiology, Lund University2008

    Haemophilus influenzae is a human specific Gram-negative respiratory tract pathogen. Encapsulated H. influenzae strains exist in six different serotypes a-f, of which type b (Hib) is the most virulent. Hib is protected by the polysaccharide capsule when invading the blood circulaton and may cause …

    lund Repository record

  3. Studies of the NAD metabolism of Haemophilus influenzae

    Kahn, David W.Virginia Polytechnic Institute and State University1985

    Haemophilus influenzae, as well as other members of the genus which require V-factor, display a unique growth requirement for intact NAD. This organism, the primary cause of bacterial meningitis, is incapable of synthesis of pyridine nucleotides from the usual precursors. An externally directed …

    vt Repository record

  4. Studies on pyridine nucleotide-dependent processes in Haemophilus influenzae

    Denicola-Seoane, AnaVirginia Polytechnic Institute and State University1989

    Haemophilus influenzae and related species have a unique requirement for externally-provided NAD; therefore, several pyridine nucleotide-requiring enzymes become important for the survival of these pathogens. Haemophilus influenzae ATP:NMN adenylyltransferase was partially purified 15-fold with a …

    vt Repository record

  5. HAEMOPHILUS INFLUENZAE AND MORAXELLA CATARRHALIS INTRA- AND INTERSPECIES QUORUM SIGNALING

    Armbruster, Chelsie ElizabethWake Forest University2011

    … instance, the leading causative agents <italic>Haemophilus influenzae</italic> and <italic>Moraxella catarrhalis</italic> are more frequently found to coexist than to be isolated individually. Polymicrobial infection and biofilm formation may have a dramatic impact on the severity and …

    wfu Repository record

  6. Survival strategies of the human respiratory tract pathogen Haemophilus influenzae

    Hallström, TeresiaMedical Microbiology, Lund University2007

    Haemophilus influenzae is an important respiratory tract pathogen responsible for a variety of infections in humans. Encapsulated H. influenzae belongs to one of six serotypes (a-f), of which type b is the most virulent one causing serious and sometimes life-threatening diseases (e.g., …

    lund Repository record

  7. Charakterisierung der initialen Aufnahme des Kofaktors V (NAD) bei Haemophilus influenzae

    Kemmer, GabrieleUniversität Würzburg

    H. influenzae ist ein fakultativ anaerobes, Gram-negatives Bakterium und wird in die Familie der Pasteurellacaea eingeordnet. Das Bakterium zeigt Auxotrophien für Hämin unter aeroben Bedingungen und für Nikotinamid-Adenin-Dinukleotid (NAD) bei aeroben wie anaeroben Wachstum. Es können zwei …

    wurz-thes Repository record

  8. A mathematical model to describe haemophilus influenzae type B within Western Australia

    Dennis, KevinEdith Cowan University, Research Online, Perth, Western Australia1995

    … likely to have on the incidence of Haemophllus influenzae Type B (HIB) and systematic HIB in Western Australia. There was a significant effort made to collect data pertinent to the estimation of parameter values but since HIB has only been a notifiable disease since 1992, there was a distinct …

    edithcowan Repository record

  9. Charakterisierung von NadR : das essentielle Enzym der NAD-Synthese bei Haemophilus influenzae

    Merdanovic, MelisaUniversität Würzburg

    I Zusammenfassung Haemophilus influenzae, ein Gram-negatives, Bakterium der Familie Pasteurellaceae, kann beim Menschen eine Vielzahl an Erkrankungen auslösen: Die bekapselte Stämme, v. a. mit Typ b Kapsel können Cellulitis, septische Arthritis, Epiglottitis und Meningitis verursachen. Die …

    wurz-thes Repository record

  10. <i>Haemophilus influenzae</i> modulins in chronic obstructive pulmonary disease airway inflammation

    Kundu, Gitanjali

    <p>Nontypeable <em>H. influenzae</em> (NTHi) causes repeated respiratory infections characterized by a brisk inflammatory response that results in the expression and secretion of proinflammatory cytokines. We hypothesized that secreted and cell asssociated NTHi proteins mediate cellular …

    emich Repository record

  11. Quorum Signaling and Biofilm Antibiotic Resistance Phenotypes of Nontypeable Haemophilus influenzae Clinical Isolates

    Reimche, JenniferWake Forest University2015

    … phenotypically diverse bacterium nontypeable <i>Haemophilus influenzae</i> (NTHi) is a leading cause of otitis media (OM). This disease affects children around the world. Treatment is complicated by the ability of the bacteria to form biofilms in which they are more tolerant to antimicrobials. …

    wfu Repository record

  12. Cloning Of HsdS Gene and Characterization of the Protein From Haemophilus Influenzae Rd

    Chalapatti, Srividya2014

    <p>.</p>

    shu-thes Repository record

  13. The Colonization Strategies of Nontypeable Haemophilus influenzae - Bacterial Colonization Factors and Vaccine Development

    Jalalvand, FarshidClinical Microbiology, Malmö, Lund University2015

    Nontypeable Haemophilus influenzae (NTHi) is a remarkably proficient colonizer of the human respiratory tract. The aim of this thesis has been to characterize currently known, and identify novel, bacterial factors involved in the key processes of colonization and pathogenesis, namely adherence to …

    lund Repository record

  14. ΜΕΛΕΤΗ ΠΑΡΑΜΕΤΡΩΝ ΕΓΚΕΦΑΛΟΝΩΤΙΑΙΟΥ ΥΓΡΟΥ ΣΕ ΘΕΡΑΠΕΙΑ ΠΕΙΡΑΜΑΤΙΚΗΣ ΜΗΝΙΓΓΙΤΙΔΑΣ ΑΠΟ HAEMOPHILUS INFLUENZAE TYPE B

    Συρογιαννόπουλος, ΓεώργιοςUniversity of Patras1987

    … AND VARIOUS TREATMENT MODALITIES IN EXPERIMENTAL HAEMOPHILUS INFLUENZAE TYPE B (HIB) MENINGITIS WERE ASSESSED. IN THE FIRST PART THE ROLE OF HIB CAPSULE AND LIPOPOLYSACCHARIDE IN THE INDUCTION OF MENNIGEAL INFLAMMATION WERE EVALUATED. A MINIMAL INFLAMMATORYRESPONSE WAS FOUND FOLLOWING …

    greece Repository record

  15. Purification and characterization of malate dehydrogenase and 6- phosphogluconate dehydrogenase from Haemophilus influenzae

    Yoon, HeejeongVirginia Polytechnic Institute and State University1988

    Haemophilus influenzae, the primary causative factor in bacterial meningitis, displays a unique growth requirement for intact NAD. Selective inhibitors of the pyridine nucleotide-requiring enzymes from H. influenzae could have a pronounced effect on growth of the organism. Haemophilus malate …

    vt Repository record

  16. Nontypeable Haemophilus Influenzae Genomes Reveal Vaccine Antigen Genetic Diversity and a Novel Host Cell Invasin

    Ahearn, ChristianState University of New York at Buffalo2019

    Ph.D.

    buffalo Repository record

  17. Dynamics of Naturally Acquired Antibody Against Haemophilus Influenzae Serotype 'A' and the Impact of Vaccination

    Konini, Angjelina2016

    Haemophilus (H.) influenzae is a human-restricted bacterial pathogen that can cause severe invasive disease. During the past two decades, the incidence of infections caused by H. influenzae serotype a (Hia) has increased in several parts of the world, particularly in Aboriginal populations of North …

    york Repository record

  18. The development of physico-chemical quality control methods for Haemophilus influenzae type b vaccine production

    Behr,Heinrich RichardDepartment of Chemistry2013

    The development of a low cost Haemophilus influenzaetype b (Hib) manufacturing platform at The Biovac Institute (TBI) required analytical method development in parallel with the production process development. Technology transfer enabled TBI to develop Hib vaccine production which could lead to the …

    cape-town Repository record

  19. Molecular Mechanisms Involved in Escherichia coli K1 and Haemophilus influenzae Type a Blood-Brain Barrier Impairment

    CAPORARELLO, NUNZIAUniversità degli studi di Catania2017

    … including Escherichia coli K1 (E. coli K1) and Haemophilus influenzae type a (Hia). During E. coli K1 meningitis, CNS cells release pro-inflammatory mediators, while the bacterium promotes the association between Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1) and p85 subunit of PI3K. …

    catania Repository record

  20. The Effect of Haemophilus influenzae and Streptococcus pneumoniae coinfection on Otitis Media Disease Progression and Treatment Efficacy

    Weimer, KristinWake Forest University2010

    … from otitis media infection are <italic>Haemophilus influenzae</italic> and <italic>Streptococcus pneumoniae</italic>. Once established, these bacteria can cause persistent and/or recurrent infections and are often refractory to antibiotic therapy. One hypothesis to explain this …

    wfu Repository record

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