Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 140 for “"Haematological"”.
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The pre-clinical evolution of haematological malignancies
Cancer-associated somatic mutations frequently drive clonal expansions in normal ageing tissues. However, the factors governing whether pre-cancerous cells transform into cancer are poorly understood, hindering identification of clones that are clinically significant rather than benign sequelae of …
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Hereditary haematological disorders in the Greek population of Cape Town
It is a recognized fact that most well defined population groups have their own typical pattern of inherited disorders. The genetic conditions most commonly found in Greek persons are the thalassaemias, glucose-6-dehydrogenase (G-6-PD) deficiency and, to a lesser extent, certain of the …
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Effect of pomegranate extracts on apoptosis and cell cycle in haematological malignancies.
Leukaemia is a complex form of blood malignancy characterized by the uncontrolled proliferation of haematopoietic cells and progressive accumulation of these cells within the bone marrow (BM) and secondary lymphoid tissues. The exact cause of leukaemia remains unknown. Leukaemia is a major problem …
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The use of aminoglycoside antibiotic therapy in neutropaenic patients with haematological disease
… of the febrile neutropaenic patient with haematological disease is difficult and often suboptimal. This study reviews the available literature to establish therapeutic guidelines in this population and then reports the use of a Bayesian statistics based predictive model to implement and …
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Applications of next-generation technologies in the diagnosis of haematological diseases and cancer
The advent of massively-parallel next-generation sequencing (NGS) methods has provided researchers with a powerful tool with which to interrogate and characterise the molecular landscape of cancer genomes. Compared to existing methods of DNA sequencing, NGS platforms generate massive amounts of …
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A study of FT-IR spectroscopy for the identification and classifcation of haematological malignancies
… as a complementary clinical tool for haematological laboratory analysis. FT-IR spectra were measured from air-dried and frozen cell lines derived from lymphoma, lymphoid, myeloid leukaemia and normal and chronic lymphocytic leukaemia blood samples. Multivariate statistical analysis was …
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Reference intervals for selected haematological and clinical biochemistry measurands in Temminck’s ground pangolin (Smutsia temminckii)
An alarming number of pangolins are currently illegally traded for their scales and meat. Many pangolins confiscated from the trade are severely clinically compromised. Unfortunately, little is known about the physiology and normal health of pangolin, making it difficult to identify disease …
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Functional Investigation of Dual αvβ3 and αllbβ3 Integrin Inhibition in Haematological and Solid Tumour Models
… cause of increased mortality. In addition, haematological malignancies (leukaemia and lymphoma) are a significant cause of morbidity and mortality in both children and adults. Therefore, new treatments which will inhibit cancer progression are required. Integrin adhesion receptors, …
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A mixed-methods study into the quality of life of adult survivors of haematological malignancies.
The treatments for haematological malignancies are often complex and intense and given over prolonged periods, leading to potentially debilitating symptoms and reduced quality of life (QoL). Those who survive can still experience long-term effects of both treatments and disease and often fear the …
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Sickle cell anaemia in Cameroon : co-inheritance of α-thalassemia, HBB gene haplotypes, clinical & haematological characterisations
… explored the correlation between α-thalassemia, haematological indices, and clinical events in Cameroonian SCA patients. Materials and Methods: For this cross-sectional study, a full blood count and clinical phenotype profile was collected for 262 Cameroonian individuals. Restriction fragment …
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Psychological, cardiovascular and haematological aspects of the type A behaviour pattern in relation to coronary heart disease
… tasks. Behavioural, cardiovascular and haematological response patterns, and the timing of reactivity, differentiated Type A's from Type B's. Whilst preparing for and following final year examinations, Type A individuals demonstrated the greater elevations in heart rate, systolic and …
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Genotoxic effects of NSAIDs and hydrocortisone in bulk and nano forms in lymphocytes from patients with haematological cancers
… in peripheral blood lymphocytes in patients with haematological cancers. The glucocorticoid hydrocortisone was also evaluated for anti-oxidant capacity. Our results demonstrate that the nano versions of each drug produced a different response than the bulk counterpart, indicating that a reduction …
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Haematological and nutritional status of Sudanese women with sickle cell trait and anaemia: does sickle cell trait compromise birth outcomes?
This research programme has investigated the haematological and nutritional status of Sudanese women who have both sickle cell trait and sickle cell anaemia and has considered whether women with sickle cell trait experience worse outcomes of childbirth than those without. Non pregnant group with …
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The anaemia of pregnancy: A report on the haematological study of 48 cases of pregnancy, with review of the literature
… to the puerperium. At the same time, full haematological investigations were carried out and the results of various types of treatment followed. The type of response to treatment was used as an important aid to the diagnosis of the type of anaemia. That the investigation of the red cell …
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A study of the Haematological findings, Serum Proteins and Liver function tests in the Natal African in Health and in Amoebiasis
A notable feature of this century has been the introduction of medical science to large, undeveloped areas throughout the world. Backward, mainly tropical, regions have become fertile fields for study, particularly of nutritional and parasitic disorders, and the application of the modern …
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