Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"HaCaT cell"”.
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The Studies for the Preparation of Platelet Lysate (PL) and the Effects of Platelet Lysate (PL) on the Proliferations for Microbial and the Human derived cells
… and proliferation of human derived cells. This study investigates the antibacterial effect of PRP gels by using the disc diffusion method on liquid PRP that has been activated by thrombin after freezing-thawing and treating with heparin. This is aimed at providing the conditions of …
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An examination of the role of IFI16 in detecting viral DNA in human immortalised keratinocytes
… infection in human immortalised keratinocytes (HaCaT). The cGAS-STING pathway was examined in IFI16(-/-) HaCaT cell lines to conclusively determine the contribution of IFI16 to DNA sensing. IFI16(-/-) HaCaT cell lines produced drastically reduced levels of interferon-b, interferon-stimulated …
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Functional study of Gap Junctional Intercellular Communication in Human Keratinocyte Cell Line
… unique membrane structures that mediate the intercellular communications among almost all tissues, are composed of connexins in vertebrate. The essential role of gap junction-mediated intercellular communications(GJIC) for coordination of cell homeostasis, tissue functions and organ development …
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The effects of TGF-β on the behaviour of a keratinocyte cell line: implications in wound repair
… of TGF-β3 on the behaviours of a keratinocyte cell line (HaCaT). Incubation with TGF-β3 increased cell spreading and appeared to reduce cell-surface contacts indicated by both SPR imaging and a detachment assay. TGF-β3 also caused a decreased cell alignment response to microcontact printed …
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RegulationofGap Junction Protein,Connexins in Immortalized Human Keratinocytes Cells(HaCaTcells)
Intercellular communication for function of cells and tissues is very important as the intracellular communication system. Gap junctions are ordered arrays of intercellular plasma membrane channels that directly link the cytosols of two adjoining cells. Gap junctional intercelluar communication …
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Molecular and microscopical analysis of pathogenic streptococci - studies on surface proteins interacting with human cells and extracellular matrix
… pyogenes has been considered as a strictly extracellular pathogen, but several studies has shown that it is capable of invading and surviving intracellularly in several human cell types. In this thesis I have investigated the interaction of S. pyogenes and Streptococcus pneumoniae (S. pneumoniae) …
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Interaction of skin cells with skin microbiota
The interaction between skin cells and skin microbiota is complicated and not fully understood. A diverse community of microbes resides on the skin that participates in shaping its physiology. Skin microbiota can modulate skin immunity and barrier, thus, contributing to skin health. Also, the …
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Screening of radioprotective agents using zebrafish and Therapeutic effects and protective mechanism of radioprotective candidates on radiation-induced oral mucositis
… key genes involved in developmental processes, cell cycle progression and proliferation, and differentiation. Unlike other vertebrate species, however, zebrafish are rapidly bred and easily maintained in the laboratory. Zebrafish embryos provide a versatile model system for assaying …
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Epidermal growth factor and Transforming growth factor α motogenic activities are mediated by Epidermal growth factor receptor : Identification of signalling pathways involved in head and neck cancer
… Growth Factor alpha (TGFα) to bind the extracellular domain of EGFR. Inhibition of this ligand binding blocks the activation of subsequent signalling pathways. It is known that not all Head and Neck cancers over-expressing EGFR respond to Cetuximab. It has been postulated that some of these …
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Crystal engineering, Bio Pharmaceutics and Cell biology of active pharmaceutical ingredient (drug) nanoparticles. Formation and cell interaction of hydrocortisone and prednisolone nanoparticles.
… nanoparticles. In the second part, cellular uptake of both coated and uncoated nanoparticles by HaCaT keratinocytes cell line was examined and indicated by quantifying the anti- inflammatory effect of nanoparticles on the LPS-induced inflammation. Also, TEM was employed to evaluate …
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Crystal engineering, Bio Pharmaceutics and Cell biology of active pharmaceutical ingredient (drug) nanoparticles. Formation and cell interaction of hydrocortisone and prednisolone nanoparticles.
… nanoparticles. In the second part, cellular uptake of both coated and uncoated nanoparticles by HaCaT keratinocytes cell line was examined and indicated by quantifying the anti- inflammatory effect of nanoparticles on the LPS-induced inflammation. Also, TEM was employed to evaluate …