Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"HXK2"”.
-
La proteína hexoquinasa 2 controla la expresión génica en saccharomyces cerevisiae por interacción proteína-proteína con el factor mediador Med8
… presencia de glucosa la proteína hexoquinasa 2 (hxk2), normalmente residente en el citosol, es translocada al núcleo donde impide la activación de la transcripción de los genes reprimibles por glucosa hxk1, glk1 y suc2 y promueve la activación de la transcripción de los genes inducidos por …
-
Metabolic engineering of yeast strains for renewable biomass utilization and valuable chemical production
… metabolism, TPS1 deletion expressed with mutant HXK2 allowed enhanced glucose or galactose fermentation. Because HXK2 also has a role in glucose signaling and repression, a mutation caused a change in this property. By deleting TPS1 and expressing mutant HXK2, yeast effectively utilized glucose …
-
Dynamic regulation of pathways by down-regulating competing enzymes
… we constructed a hexokinase valve where Hxk2 and GIk1 were deleted and the only remaining Hxk1 was placed under control of the tetracycline transactivating system (tTA) that enables repression of Hxk1 up to 10-fold in activity upon addition of doxycycline. Downregulation of this competing …
-
The Regulation of the Phosphatidate Phosphatase Gene <em>PAH1</em> and Its Regulatory Role on Cell Homeostasis
… biosynthesis pathway. Interestingly, the <em>HXK2</em> gene was the only gene tested that was downregulated in <em>pah1Δ </em>cells. Since <em>HXK2 </em>is involved in preventing apoptosis, this implied that Pah1p might be involved in cellular apoptosis. Additional growth experiments on …