Global ETD Search
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Showing 1 to 2 of 2 for “"HV4"”.
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T Cell Receptor Alpha Chain Residues Involved in Antibody Binding and Recognition of peptide/MHC Ligand
… is analogous to the fourth hypervariable region (HV4) of the $\beta$ chain, disrupted binding to QL9/L$\sp{\rm d}$ approximately five-fold. Based on these results and a homology model of the 2C $\alpha$ chain variable region, these five residues are likely to be involved in either stabilization of …
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Butyrophilin family genes as putative coeliac disease risk loci
… from the γδ T cell side. The germline-encoded HV4 loop of the duodenal Vγ4+ γδ TCRs were examined, that can directly bind the BTNL3 proteins (15, 16). However, no significant differences were found between the HV4 amino acid sequences of 141 CeD and 238 normal samples. Next, the variation in …