Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"HTLV"”.
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HTLV-1 bZIP FACTOR ACTIVATES MYOFERLIN EXPRESSION TO FACILITATE HTLV-1 INFECTION AND MIGRATION OF INFECTED T-CELLS
Human T-cell Leukemia Virus type 1 (HTLV-1) is a complex retrovirus responsible for diseases such as Adult T-cell Leukemia (ATL) and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). The viral protein HBZ is consistently expressed in infected individuals and plays a crucial role …
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Vivenciando a sexualidade e a incontinência urinária: histórias de mulheres HTLV positivas
… mulheres com incontinência urinária (IU), sendo HTLV positivas e identificar as estratégias utilizadas por essas mulheres para exercer a sexualidade. Tais objetivos foram alcançados por meio da pesquisa qualitativa, tendo a história oral temática como método utilizado. A técnica para coleta das …
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Study of the DNA Damage Complexes Within the HTLV-1 Tax Oncoprotein Interactome
<p>Human T-cell leukemia virus type 1 (HTLV-1) is a transforming retrovirus that can give rise to adult T-cell leukemia (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Tax is a virally encoded oncoprotein that is involved in HTLV-1 mediated cellular transformation. It …
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Mutational analysis of the human histone chaperone, Nap1, in nucleosome disassembly at the HTLV-1 promoter
… uses human T-cell leukemia virus, type 1 (HTLV-1) as a model for studying eukaryotic transcription activation and gene regulation. Previous studies using chromatin immunoprecipitation to look at the HTLV-1 promoter have correlated transcription activation with a decrease in …
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Die Spezifität der systemischen und intrathekalen Immunantwort bei der Infektion mit dem humanen T-lymphotropen Virus 1 (HTLV-1)
Das Retrovirus HTLV-1 induziert eine Myelitis, die HTLV-1 assoziierte Myelopathie / tropische spastische Paraparese (HAM/TSP) genannt wird. Bei dieser chronisch entzündlichen Erkrankung des ZNS infiltrieren HTLV-1 infizierte CD4+ T-Lymphozyten das Rückenmark und exprimieren retrovirale Proteine. …
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Deephtlv: A Deep Learning Framework For Detecting Human T-Lymphotrophic Virus 1 Integration Sites
… called human T-lymphotrophic virus type 1 (HTLV-1). Since then, HTLV-1 has been identified as the causative agent behind several diseases such as adult T-cell leukemia/lymphoma (ATL) and a HTLV-1 associated myelopathy or tropical spastic paraparesis (HAM/TSP). As part of its normal …
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Regulation of Human T-cell Leukemia Virus Type 1 Infection and Replication
… Currently, there is no known receptor for HTLV-1, though a number of factors that enhance entry have been identified. In an effort to identify a cellular receptor or attachment factor for HTLV-1, we carried out a retroviral cDNA library screen, in which cDNA from permissive HeLa S3 cells …
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Characterization of Human T-Cell Leukemia Virus 1 Reverse Transcriptase
<p>Human T-cell leukemia virus 1 (HTLV-1) is a type C human retrovirus which has been the causative agent of Adult T-cell leukemia. Replication of the retrovirus; requires a reverse transcriptase which converts the retroviral RNA into DNA which is later incorporated into the host's genome. Very …
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Darifenacina versus Estimulação Elétrica Transcutânea Parasacral para Tratamento da Síndrome da Bexiga Hiperativa Neurogênica em Individuos Infectados pelo HTLV-1
… approximately 78% of individuals infected with HTLV-1 with associated myelopathy and in 59% of infected individuals without motor impairment. Anticholinergic medications are widely used to treat OAB symptoms, but the frequency of adverse events such as constipation, dry mouth, visual and mental …
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Isolation and Functional Mapping of Human T-Cell Leukemia Virus Type 1 Tax Oncoprotein DNA-Damage Complexes
<p>Human T-cell Leukemia Virus Type 1 (HTLV-1) is a transforming retrovirus which causes Adult T-cell Leukemia (ATL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). Cellular transformation can be caused by a single viral <em>trans</em>-activating protein, Tax. Tax may …
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Subcellular Localization of Human T-cell Leukemia Virus Type 1 Tax Oncoprotein
<p>Human T-cell Leukemia Virus Type 1 (HTLV-1) is a transforming retrovirus that gives rise to Adult T-cell Leukemia (ATL) and a variety of other subneoplastic conditions such as HTLV-Associated Myelopathy/Tropical Spastic Paraperesis (HAM/TSP). In ATL, the transformation and immortalization of …
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Studying viral-like particles using fluorescence fluctuation spectroscopy
… extension of FFS to study the human retrovirus HTLV-1 will be covered. Studying HTLV-1 and comparing the results to our studies of HIV-1 provides hints about which features are common among retroviruses and which features are virus specific. In previous FFS studies of VLPs, we focused on a …
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Quantitative Fluorescence Studies in Living Cells: Extending Fluorescence Fluctuation Spectroscopy to Peripheral Membrane Proteins
… insight into the early assembly steps of the HTLV-1 retrovirus.
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Marcadores periféricos de dano ao sistema nervoso central : a proteína S100B e atividades ecto-nucleotidásicas
… síndrome de Down, mielopatia associada ao vírus HTLV-I, lupus eritematoso sistêmico, epilepsia secundária a neurocisticercose e, além disso demonstramos a curva de ontogenia da S100B no sangue. Na segunda parte descrevemos uma atividade de nucleotidases presente em líquor de ratos, e finalmente, …
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New Targets of p53 Regulation: From Aging to Immune Response
… high degree of homology with the exogenous virus HTLV-1. I observe the upregulation of human endogenous retroviral envelopes in response to p53 activation. I hypothesize that the expression of endogenous retroviruses may serve as a marker of oncogenic stress in prostate cancer with diagnostic …
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Retroviral envelope glycoproteins: mediators of neuropathology in nervous system development and neurodegeneration in HIV-1 infection
… virus, are clinically similar to HIV-1 and HTLV-1 (human T-lymphotrophic virus), respectively. Like gpl20 of HIV-1, the envelope glycoprotein of FeLV produces lymphocytic and neuronal toxicity. In the first study of this dissertation, we hypothesized that retroviral envelope glycoproteins …
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Untersuchungen zur Rolle von zytotoxischen Molekülen bei der Immunabwehr gegen Retroviren
… Infektionen des Menschen, wie HIV und HTLV. Ihre molekulare Wirkweise war bisher aber nicht bekannt. Die Infektion von Mäusen mit dem retroviralen Friend Virus Komplex (FV) wurde daher als Modell verwendet, um die antiviralen Mechanismen gegen Retroviren aufzuklären. Als erstens wurde …
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