"HTH-turn mimic." · 2 results · Global ETD Search

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Showing 1 to 2 of 2 for “"HTH-turn mimic."”.

Part 1 Synthesis of a potent histone deacetylase inhibitor; Part 2 Studies towards a stabilized helix-turn-helix peptide

Liu, TaoVirginia Tech2007

… in the design of HDIs. The hydrophobic cyclic turn mimic allows the formation of a tight complex between HDI and HDAC enzymes. The second part of this work is to synthesize secondary structure mimics and incorporate them into the helix-turn-helix (HTH) motif. One of the important methods to …

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I. Collagen-like polypeptides. II. Helix-turn-helix peptides and turn mimetics

Dai, NanVirginia Tech2008

… of the collagen triple helix. The helix-turn-helix motif is an important tertiary structure in DNA-binding proteins. Stepwise modifications of the Antennapedia HTH peptide (27-55) were performed to improve the helicity and stability. The peptide with more side-chain ion-pairs was over 4 …

vt Repository record for I. Collagen-like polypeptides. II. Helix-turn-helix peptides and turn mimetics (opens in a new tab)