Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"HSIL"”.
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T-cell responses to human papillomavirus in men with anal high-grade squamous intraepithelial lesions
… high-grade squamous intraepithelial lesion (HSIL). Unlike cervical cancer, the natural history of anal HSIL is poorly understood, and there is little evidence to inform prevention guidelines. In a retrospective audit of 574 men (73% HIV-infected) attending our anal cancer screening clinic, …
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Detecting cervical dysplasia with quantitative spectroscopic imaging
… high-grade squamous intraepithelial lesions (HSIL) from non-HSILs (less severe conditions) in cervical transformation zone. This is a clinically important distinction because HSIL requires treatment. The results show measuring the per-patient normalized reduced scattering coefficient alone …
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Quantitative spectroscopy for detection of cervical dysplasia
… of high-grade squamous intraepithelial lesions (HSIL), which are precancerous lesions with high risk of progression. Colposcopy, even when conducted by experts, is subject to significant diagnostic variability. The aim of the work presented in this thesis was to develop a non-invasive clinical …
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Histological outcome of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (asc-h) papanicolaou smears diagnosed at Groote Schuur hospital
… High grade Squamous Intraepithelial neoplasia (HSIL) that lies between Atypical Squamous Cells of Uncertain Significance (ASC-US) and HSIL. Aim: The aim of this study was to assess the histological outcome of the ASC-H Papanicolaou smears diagnosed between January 2009 and December 2019 and to …
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Natural History of Human Papillomavirus Infections and Other Sexually Transmitted Infections in Rwanda-Immunological Aspects of the Uterine Cervix
… squamous intraepithelial lesions (LSIL and HSIL) and cancer and associated risk factors in 400 HIV- and HIV+ Rwandan women. Whether HPV testing could serve as a screening method for detecting HSIL was analyzed. We also assessed the prevalence and curing rates of different sexually …
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Risk factors and diagnostic methods of high grade cervical squamous intraepithelial lesions /
… cervical squamous intraepithelial neoplasia (HSIL) of women residing in particular areas employing the method of questionnaire surveys. The following risk factors were identified: not getting vaccinated against flu, living in villages and other rural areas, primary or special secondary …
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Evaluating the role of PLGF and VEGFR-1/ Flt-1 in the development of cervical intraepithelial neoplasia and invasive cervical carcinoma in the background of HIV infection in women living in South Africa
… (LSIL) to high grade intraepithelial lesions (HSIL) and invasive carcinoma remain incompletely understood. Angiogenesis within the tumour microenvironment, mediated by placental growth factor (PLGF) and its receptor vascular endothelial growth receptor (VEGFR1/Flt-1), has been implicated in …
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Long-term outcomes of women treated for high-grade squamous intraepithelial lesions at a University Hospital colposcopy unit in South Africa. A 5-year retrospective cohort study
… with high grade squamous intraepithelial lesion (HSIL) Pap smears seen at GSH colposcopy clinic between 01 January 2010 and 31 December 2015. The outcome measures were; diagnostic concordance between cytology, colposcopy and histology, large loop excision of the transformation zone (LLETZ) and …
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Estudio de la profundidad de conización mediante LLETZ y la persistencia de lesión precursora de cáncer de cérvix y de infección por VPH postconización.
… en las pacientes sometidas a conización por HSIL (High Squamous Intraephitelial Lesion), mediante LLETZ en el servicio de Ginecología del Complejo Hospitalario Santa Lucía-Santa María del Rosell de Cartagena (CH). MÉTODOS Se ha realizado un estudio observacional, transversal, retrospectivo en …
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Factores genéticos pronósticos y de susceptibilidad en el cáncer de cuello de útero.
… una lesión intraepitelial de alto grado (HSIL), que puede acabar desarrollando un cáncer invasivo. Se cree que en esta discriminación juega un papel importante la susceptibilidad genética de cada paciente. Esta podría estar relacionada con genes involucrados en la respuesta inmune entre …
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Expressão do fator inibitório da migração de macrófagos e do fator de permeabilidade vascular em lesões da cérvice uterina induzidas pelo papilomavírus humano
… highgrade squamous intraepithelial lesion (HSIL) type. The overall prevalence rate of genital HPV infection was 80%, with 86.1% in patients with lesions. Mean VEGF and MIF expression increased gradually when compared to normal patients, LSIL and HSIL, respectively, corresponding to the …
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Papillomavirus humanos 16 y 18: prevalencia en lesiones cervicales, marcadores virales de progresión
… de alteraciones citológicas de alto grado (HSIL) y un VP positivo del 97% en HSIL. CONCLUSIONES: 1. VPH16 es el genotipo más frecuente en CIN2+; VPH31, 33, 35, 45, 51, 52, 56 y 58 también son comunes, sugiriendo que son necesarias vacunas frente a más genotipos. 2. Debido a la alta …
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Apoyo en el diagnóstico temprano de cáncer cervical mediante procesamiento de imágenes microscópicas de citología
… Las células anormales incluyeron muestras LSIL, HSIL y carcinoma. En una etapa subsiguiente, se llevaron a cabo recortes unicelulares, los cuales fueron sometidos a un proceso de pre-procesamiento con el objetivo de mejorar la calidad de la imagen, eliminando ruido u otros factores externos que …
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The natural history of low grade squamuous intra-epithelial lesions (LSIL) in women attending Groote Schuur Hospital Colposcopy Clinic
… likely to regress and none of them progressed to HSIL [p=0.002]. Those using an IUCD made up 141 person-months studied, they were shown to have a 6 times greater likelihood to result in regression (p=0.01) compared to women on no contraception. Conclusion: The high regression and low progression …
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Hygiena Study: audit of women managed with Cone Biopsy at Groote Schuur Hospital from 1st April 2013 to 31st October 2015
… of the women had high-grade disease (CIN 2/3 or HSIL) and 12,5% (47/376) had microinvasion. Ectocervical margins were clear in 57,6% (212/368) of cases and endocervical margins were clear in 54,6% (201/368) of specimens. Fifty-one cancers were detected during the study period. In the multivariate …
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VPH y carcinoma de cervix. Factores de progresión viral
… 31 y 35 años tuvieron significativamente más HSIL que las menores de 30 años (p=0.02). El 64.4% de las pacientes necesitaron al menos una intervención quirúrgica para eliminar la infección. Las pacientes que presentaban lesiones de alto grado evolucionaron peor que el resto (p<0.0001). …
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The prevalence of different human papillomavirus genotypes in lesions of the uterine cervix as a method in risk assessment of cervical cancer
… 31 at 14%. Among high-grade precursor lesions (HSIL and AGC) on cytology HPV 16 was the most frequently detected genotype, accounting for 33% of the total genotypes identified, followed by HPV P3 (HPV types 35/39/68) [17%], HPV 52 (11%), and HPV P1 (HPV types 33/58) [9%]. V The other high-risk …