Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"HRG"”.
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Investigating the invasive and cytoprotective properties of the heme binding protein HRG-1 in cancer cells
This thesis investigates the mechanisms by which HRG-1 contributes to the invasive and cytoprotective signalling pathways in cancer cells through its effects on VATPase activity and heme transport. Plasma membrane-localised V-ATPase activity correlates with enhanced metastatic potential in cancer …
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The role of EGFR, HER 2-4, heregulin and downstream signalling in prostate adenocarcinoma
… as positively prognostic in HSPC. Heregulin (HRG), a principle HER family ligand, has previously been noted to have a differential effect on HSPC (decreased proliferation) and HRPC (increased proliferation) cell lines. This study determines influence of HER family and HRG in a larger HSPC …
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Effects of Heregulin on Muscle: A Biochemical and Histological Analysis
… muscular dystrophy. Heregulin/neuregulin-1 (HRG), a member of the epidermal growth factor family has been shown to induce neuromuscular junction (NMJ) gene expression in vitro and improve skeletal muscle function in dystrophic mice. However, it is unclear if the HRG effects were due to …
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Towards the development of a horizontal ribbon growth process to produce thin, monocrystalline silicon sheets via the stabilization of the (111) plane in undercooled melts
… for decades, only the Horizontal Ribbon Growth (HRG) process has ever demonstrated monocrystalline silicon ribbons. Unfortunately, these ribbons have been too thick for commercial use and the HRG process model cannot explain either its inability to produce thin ribbons or what conditions …
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The regulation of RANK and RANKL mRNA expression through activation of the JAK2/STAT5a pathway in human breast cancer cell lines ©
… growth factor (EGF) and heregulin-beta1 (HRG-1), all known to activate STAT5a and play a role in breast cancer progression. This study shows that RANKL expression is upregulated by PRL, EGF and HRG-1, and that PRL and HRG-1 regulate transcription through the JAK/STAT5a pathway.
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Investigating the polyphosphate interactome with lysine- and histidine-rich proteins
… HPM target protein, histidine-rich glycoprotein (HRG) to which we uncovered that HPM reduced its ability to bind IgG1. Moreover, we demonstrate that S100A9, a known ligand of HRG, is prone to multimerization in the presence of polyP. Though the physiological relevance of both HPM and KPM remain …
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A Hierarchical Algorithm for Probabilistically Complete Path Planning in Multi-Floor Environments
… the 2D maps. This work proposes a new algorithm, HRG*, for probabilistically complete and asymptotically optimal multi-floor path planning that carries these guarantees, together with a reference implementation whose performance is characterized in comparison to the native version.
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Characterization of the Transition Region in the QCD Phase Diagram
… calculated in the Hadron Resonance Gas (HRG) model to experimental data to determine the chemical freeze-out temperature, with particular attention on the dependence of such temperature on the flavor composition of the particles. A separate analysis is performed to study the content of …
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Reconstrucción de grafos hiperbólicos aleatorios
… de grafos hiperbólicos aleatorios (HRGs, por su sigla en inglés) radica en que estos son buenos modelos de redes complejas del mundo, tales como las redes sociales. En la literatura existen escasos trabajos que abordan el problema de reconstrucción de grafos aleatorios. No …
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STRONGLY INTERACTING MATTER:ANALYSIS OF QCD PHASE DIAGRAM BY THERMODYNAMIC GEOMETRY
… states. I applied this method to LATTICE QCD and HRG models, to Nambu-Jona Lasinio model, and to study the effect of fluctuations in Quark-Meson model, and it is the first application of thermodynamic geometry to field theory at finite temperature and density. The phase transition has been studied …
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THE OMEGA-6: OMEGA-3 FATTY ACID RATIO IN SWINE NUTRITION: LONG-TERM EFFECTS ON PERFORMANCE, MILK FATTY ACID PROFILES, OXIDATIVE STATUS, AND PROTEOMES
… APOB, APOE); pro-coagulation proteins (F2, HRG, ORM1); coagulation regulator (PLG); and APPs (HP, ITIH4, TF, SAA, SERPINA1). These proteins participate in platelet metabolism, haemostasis, and cross-talk between coagulation pathways and inflammation, particularly in the innate immune system. …