Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"HR1"”.
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Structural and Biochemical Characterisation of the HR1 domains of the Protein Kinase C-related kinase family
… PRKs have three N-terminal Homology Region 1 (HR1) domains, HR1a, HR1b and HR1c. These are predicted antiparallel coiled coils which interact with the Rho proteins. While HR1a and HR1b domains have been studied in vitro, very little is known about the HR1c domain. This project aims to provide …
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Charakterisierung membranverankerter HIV-Fusionsinhibitoren
… Aminosäureaustausch (BaL, N126K) bzw. einem in HR1 liegenden Aminosäureaustausch (NL4.3, L33S) vermittelt. Im Fall von BaL trat gleichzeitig eine Punktmutation in HR1 (I48V) auf, die die Resistenz moduliert. Obwohl keine dieser Mutationen im mit T-20 Resistenz assoziierten Motiv lag, war die …
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Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP
… The solution NMR structure of the Cdc42 binding HR1 domain of TOCA1 provides the first structural data on this protein and reveals some interesting structural features that may relate to binding affinity and specificity. A structural model of the Cdc42-HR1 complex provides further insight into …
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Biological activities and antidiabetic potential of novel peptides from frog secretions
… and four tigerinin peptides (Tigerinin-HR1 to Tigerinin-HR4), they exhibited distinct biological activities. <br/><br/>In Chapter 3, the detailed function and correlative mechanisms of novel phylloseptin peptide Phylloseptin-PBu were described. We showed that Phylloseptin-PBu could …
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100% container scanning : security policy implications for global supply chains
… 3, 2007, President George Bush signed into law HR1 the "Implementing Recommendations of the 9/11 Commission Act of 2007." The 9/11 Act requires 100% scanning of US-bound containers at foreign seaports by 2012 through the use of non-intrusive (NII) and radiation detection equipment. Maritime …
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Design of a Linear Ultrasonic Piezoelectric Motor
… characteristics of the benchmark Nanomotion HR1. The model predicted a linear motor capable of pushing up to 5 N and a maximum speed of 0.4 m/s. A prototype frame was built out of tool steel and run against an oxide ceramic plate. The USM prototype's piezoelectric elements did not provide the …
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PART I CRYSTAL STRUCTURE OF A DIMERIZATION DOMAIN OF DROSOPHILA CAPRIN. PART II CHARACTERIZATION OF TWO CAS13B CRISPR-CAS SYSTEMS FROM PORPHYROMONAS GINGIVALIS
… Melanogaster Caprin (dCaprin) shares conversed HR1 domain with Caprin protein family members, which are RNA binding proteins that play critical roles in many important biological processes, such as synaptic plasticity, stress response, innate immune response and cellular proliferation. One of …
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Experimentelle und theoretische Studien zur Einsetzbarkeit von Carbokationen in der organischen Synthese
… 62 6364 65 6641MeMeOMeOR1R2ZnCl2OMe68 Me HH HR1 R2H Me61, 6462, 6563, 66 Schema 0-2: Bildung von Cycloaddukten ausgehend von 41. Die Kinetik der Reaktionen von 41 und 42 mit one-bond Nucleophilen wurde UV-spektroskopisch untersucht. Dadurch konnten die Elektrophilieparameter der beiden …