Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"HPV-18"”.
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MOLECULAR PERSPECTIVES OF THE EPIDEMIOLOGY, EVOLUTION AND TAXONOMY OF HUMAN PAPILLOMAVIRUSES
… and databases for the reliable assessment of HPV genomes from lesions, through the use of Polymerase Chain Reaction (PCR) and nucleotide sequencing. Conservation of 30 amino acids in a selected 450 bp L1 fragment unequivocally identifies fragments derived from HPV genomes. Nucleotide sequence …
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RAR beta trans-repression of AP-1 transcription factor in HeLa cervical cancer cells : consequences on transcription of viral and cellular AP-1 controlled genes
… For this purpose, human papillomavirus HPV-18 positive HeLa cells were stably transfected with RARß2 cDNA under the control of the ß-actin promoter. The characterization of the RARß2 tranfectants revealed a strongly reduced AP-1 binding to the corresponding specific oligonucleotides, …
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The prevalence of different human papillomavirus genotypes in lesions of the uterine cervix as a method in risk assessment of cervical cancer
… persistent infection with Human Papillomavirus (HPV), a sexually transmitted, oncogenic virus. There are more than 100 different HPV genotypes. Of these, studies have largely shown that the high- risk types 16 and 18 account for most cancers. However, with improved screening methods, other …
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Vegetable intake and head and neck cancer
… subtype of HNC, has become the leading site for HPV-associated cancers in humans and causing ∼70% of all OPSCC in the United States. HPV infection alone may not be sufficient to cause OPSCC, requiring the presence of other factors such as smoking or chewing tobacco, high-risk sexual behavior, and …
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Molecular analysis and application of tissue microarray technology to the histopathological and immunohistochemical analysis of cervical adenocarcinoma
… of cervical adenocarcinomas. The prevalence of HPV 16&18 in cervical adenocarcinoma cases was assessed to evaluate its relation to cervical adenocarcinoma. Using haematoxylin and eosin staining method 273 samples (blocks) were obtained from 177 biopsies composed of 16 normal cervical biopsies, …
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Indentification and molecular characterization of human papillomavirus infection among women living with and without HIV in selected health facilities in Limpopo Province, South Africa
Background: Co-infection of human papillomavirus (HPV) and human immunodeficiency virus (HIV) has been well established. Both viruses are sexually transmitted with paramount public health implications due to their interaction with cervical cancer (CC). Globally, the estimated prevalence of HPV is …
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Affordable technologies for point-of-care diagnostics
… relevant viral loads human papillomavirus (HPV) from clinical samples. In the next part of my work, I built an optical setup using off-the-shelf parts for the inexpensive detection of a fluorescent progesterone biosensor; next, I translated this solution-based progesterone biosensor into a …
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Transcriptional Regulation Mediated by Human Papillomavirus E2 Protein
Human papillomaviruses (HPVs) are one of the most common sexually transmitted pathogens in the world. The American Social Health Association reports that there are at least 20 million Americans already infected with HPVs and approximately 5.5 million new cases are reported annually. In HPVs, …
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Desenvolvimento de um biossensor amperométrico de DNA para detecção do Papilomavírus humano
… grave no Brasil e no mundo com cerca de 18.680 mulheres infectadas anualmente. O Papilomavírus Humano (HPV) tem sido biologicamente associado ao desenvolvimento de lesões cervicais, devido a sua capacidade de infectar células epiteliais, e progressão ao câncer do colo de útero. O …
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Towards the development of plant-made PsVs as potential delivery vehicles for therapeutic HPV vaccines
Infection with human papillomavirus (HPV) is the leading cause of cervical cancer, the fourth most common cancer in women globally. Cervical cancer results in an estimated 604,000 new cases and 342,000 deaths each year, with the majority of these cases reported in sub-Saharan Africa. HPV-16 is a …
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Human Papillomavirus DNA extraction and genotype analysis by multiplex real time polymerase chain reaction from formalin fixed paraffin wax-embedded cervical carcinoma specimens
… infection by high risk human papillomavirus (hrHPV) genotypes. The exact type of hrHPV varies geographically and is the basis for HPV–based vaccination for cervical squamous cell carcinoma prevention. Little is known regarding local hrHPV genotypes within the Western Cape population of South …
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Chlamydia trachomatis diversity and pathogenesis in young South African women, related to HPV prevalence and risk
… trachomatis (CT) and human papillomavirus (HPV) infections are particularly prevalent among younger demographics, with young women experiencing higher rates of infection compared to men. Due to these often being asymptomatic, both CT and HPV infections are challenging to detect in the …