Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"HPV Vaccines"”.
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Towards the development of plant-made PsVs as potential delivery vehicles for therapeutic HPV vaccines
Infection with human papillomavirus (HPV) is the leading cause of cervical cancer, the fourth most common cancer in women globally. Cervical cancer results in an estimated 604,000 new cases and 342,000 deaths each year, with the majority of these cases reported in sub-Saharan Africa. HPV-16 is a …
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Perceptions of the Role of the Oral Healthcare Providers in HPV-related Oral Cancer Education and Advocacy for the HPV Vaccine
… increasing prevalence of human papillomavirus (HPV) infections and subsequent HPV-related oral cancers has uncovered the need for more focused attention on the negative consequence of the exclusion of oral healthcare from overall healthcare. A review of the existing literature related to …
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The Immunogenicity of Plant-produced Human Papillomavirus (HPV) Virus-like particles (VLPs) in Mice
… infection with high-risk Human papillomaviruses (HPVs). It is ranked fourth among the top cancers in women worldwide, with ~87% of the global cervical cancer cases reported in developing countries. The HPV L1 capsid protein can self-assemble into virus-like particles (VLPs) that are structurally …
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Making evidence, making legitimacy : the introduction of HPV (Human Papillomavirus) vaccines in Colombia
… with specific types of Human Papillomavirus (HPV). There are currently two vaccines which protect against the HPV types associated with 70% of cervical cancers. In 2013 the Colombian government introduced Gardasil® (Merck’s HPV vaccine) into the Colombian Expanded Programme of Immunisation. …
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Use of the health belief model to understand HPV vaccine behavior in female undergraduates
<p>Human papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the US and causes several cancers. HPV vaccines can protect individuals against multiple HPV strains that can cause certain cancers. Despite the benefits, 51% of college women have received the HPV vaccine. The …
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Cervical Cancer at the Crossroads. An historical ontology of evidence in cervical cancer prevention
… of the causal role of Human Papillomavirus (HPV) in cervical cancer has prompted shifts in policies and practices, with new HPV vaccines and tests being gradually introduced into health services worldwide. Empirically, this thesis is based on archival research and qualitative interviews with …
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Novel intranasal GNRs-DNA vaccines against human papillomavirus infection
Currently licensed HPV vaccines, Cervarix and Gardasil, have been successfulin preventing HPV infection and high-graded cervical intraepithelial neoplasia (CIN2,3) in school girls in the UK and other developed countries. However, their high costshave hindered their wider use in preventing HPV …
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Longitudinal Keratinocyte Proliferation Induced by Human Papillomavirus 16E6 and NFX1-123 Partnership
High-risk human papillomaviruses (HPV) cause cervical, anogenital, and head and neck cancers. Despite the availability of preventive HPV vaccines, their poor uptake leaves most men and women at risk for these cancers, many of which remain common globally and others that are increasing domestically. …
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Cervical Cancer in the USA: Prevention, Detection, and Disease Outcomes in Relation to Novel Factors and Disparities
Due to the availability of HPV vaccines and cervical cancer screening services in the United State (USA) cervical cancer has recently become preventable given adequate healthcare infrastructure and women's ability and willingness to follow health guidelines. Any case of invasive cervical cancer …
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Characterisation of human surfactant protein A and recombinant human vimentin in their modulation of HPV16 pseudovirus infection
Infection by oncogenic human papillomavirus (HPV) is the primary cause of cervical cancer, where low-and middle-income countries (LMIC) have the highest incidence. Prophylactic HPV vaccines exist but LMIC have limited access. Therefore, alternative preventative measures against HPV infection and …
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Quasivirus Infection Model Identifies a Novel Role for Protein Arginine Methyltransferase 1 in the HPV Lifecycle
… mammals, birds, reptiles, and fish. Over 400 HPVs have been identified and these viruses fall into 5 genera termed Alpha-papillomaviruses, Beta-papillomaviruses, Gamma-papillomaviruses, Mu-papillomaviruses, and Nu-papillomaviruses. The Alpha-papillomaviruses genus contains a subset of HPVs …
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A study of the immune response to human papillomavirus types causing cervical cancer
… the antibody responses to human papillomavirus (HPV) proteins and the association of these responses with cervical disease. Immunoglobulin G (IgG) antibodies to HPV antigens were measured by enzymelinked immunosorbent assay (ELISA) in the serum of children, female blood donors, and patients with …
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Adolescent immunisation in Africa in the decade of vaccines
… benefits from immunisation. In the decade of vaccines (2011-2020), adolescent immunisation is a topical subject. An up-to-date and synthesized research on adolescent immunisation is lacking. Overall purpose: The purpose of the PhD thesis was to characterize adolescent immunisation in the …
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HPV vaccination: knowledge, attitudes and beliefs in the Chinese population
… related to infection by Human Papilloma Virus (HPV): effective HPV vaccines have been developed and vaccination programmes introduced in many countries over the last decade. Given the burden of cervical cancer in China, it is imperative that effective primary and secondary prevention strategies …
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Prevalence of Human papillomavirus among women following HPV vaccine introduction; a systematic review
… have been made by some countries to offer HPV vaccination since its introduction in 2006. Population effectiveness of HPV vaccines is presently an active area of research. We review available evidence on the effectiveness of HPV vaccine uptake among female adolescents to prevent HPV …
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Effects of Oncostatin-M Receptor overexpression on cervical squamous cell carcinoma cells and their extracellular vesicles
… screening and introduction of prophylactic HPV vaccines have drastically decreased incidence rates in high income countries. However, it is still one of the leading causes of cancer morbidity in middle and low income countries and the prognosis for advanced or recurrent cervical carcinoma …
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Rerouting Pre-Existing Host Vaccine-Induced Immunity to wards Breast Cancer
… targeting immune checkpoint pathways and HPV vaccines has renewed hope that patient survival can be increased through enhancing T-cell responses. We propose to test a novel approach that may bypass host immune tolerance to cancer cells. We hypothesize that host T-cell immunity acquired …
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Development of recombinant immunotoxins targeting overexpressed cell surface biomarkers trophoblast cell-surface antigen 2 and mesothelin for cervical cancer treatment
… high-risk strains of the human papillomavirus (HPV). Despite the availability of HPV vaccines and early detection methods such as Pap smears and HPV testing, many women remain undiagnosed or only receive treatment in advanced stages of the disease in low- and middle-income countries (LMIC). The …
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HPV pseudovirion production in plants
Human papilloma virus (HPV) infection is the most common etiological agent of cervical cancer, the most common cancer in women in Africa. The lifecycle of HPV has historically made the virus difficult to culture in vitro, and this has hindered the study of the virus, as well as development of …