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Showing 1 to 10 of 10 for “"HPLC technique"”.
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Chemical composition and fiber structure as factors affecting fiber fermentation
… and a high performance liquid chromatographic (HPLC) technique for the analysis of monosaccharides was developed. Procedures using sulfuric acid as the hydrolytic agent were superior compared to a procedure using trifluoroacetic acid. The HPLC technique, involving anion exchange chromatography …
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Molecular interactions in pharmaceutical preformulation and supramolecular complexes. Structural properties governing drug-plasma protein binding and investigation of amino acids co-crystals
… The High-Performance Liquid Chromatography (HPLC) technique was used in the current study to assess drug-PPB interaction. Using Michael Abraham’s ‘Linear Free Energy Relationship’ (LFER) method, two major plasma proteins namely, Human Serum Albumin as HSA and α-1-Acid Glycoprotein as AGP, …
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Molecular interactions in pharmaceutical preformulation and supramolecular complexes. Structural properties governing drug-plasma protein binding and investigation of amino acids co-crystals
… The High-Performance Liquid Chromatography (HPLC) technique was used in the current study to assess drug-PPB interaction. Using Michael Abraham’s ‘Linear Free Energy Relationship’ (LFER) method, two major plasma proteins namely, Human Serum Albumin as HSA and α-1-Acid Glycoprotein as AGP, …
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Desymmetrilizing Organic Molecules via Structural Functionalization
… dialdehydes as well as their monitoring by using HPLC technique. The synthesis of dialdehydes was also carried out under modified conditions to give good yields. The resulting mono controlled products are very useful for organic synthesis and for pharmaceutical industry. The related mechanisms …
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Lipoidal species in ocular spoilation processes
… study was to develop analytical techniques capable of analysing the minute quantities of biological deposition involved, in particular the lipid fraction. Prior to this work such techniques were unavailable for single contact lenses. It is envisaged that these investigations will …
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The adsorptive properties of oligomeric, non-ionic surfactants from aqueous solution
… of the surfactants were characterised using the HPLC technique. Two gradients were used: a normal phase gradient was used to study the surfactants from non-aqueous solution; an unusual gradient, which could not be definitively categorised as either normal or reversed phase and which was developed …
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Pharmacokinetic Profiles of Oxytetracycline in Yellow Perch (Perca flavescens) as Determined by Plasma Concentration Following Different Routes of Administration
… of a high-performance-liquid-chromatographic (HPLC) technique, the plasma OTC concentrations were determined for each of the four routes of administration. Plasma concentrations were also evaluated in yellow perch exposed to a static 48-hour OTC water bath (100 mg/l). The terminal half-lives …
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Multifunctional Liposomal Carriers Encapsulating Temozolomide, RG7388 and Elacridar for Targeted Glioblastoma Multiforme Therapy
… acid conjugate for the tumour cell targeting. An HPLC technique was developed and validated for the simultaneous detection and quantification of temozolomide, elacridar and RG7388 and it was found to obey USP validation parameters for specificity, linearity, accuracy and precision. This method was …
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The role of nitric oxide in pre-eclampsia
… chloride ions. Successive improvements to the technique involved changing the elution system to a gradient, initially to one with carbonate and subsequently to chloride, changing the detector system to direct UV detection at 214nm and changing the column to a high capacity, strong exchanger …