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Showing 1 to 1 of 1 for “"HPD/SVN motif"”.
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Characterization of Plasmodium falciparum PFF1010c and screening of pyrimidine-quinoline hybrids as inhibitors of HsP70-HsP40 functional partnerships of the Malaria parasite
… function of PFF1010c. Notably, PFF1010c possess SVN residues in place of the HPD motif located in the so-called J domain of this Hsp40 co-chaperone. For this reason, PFF1010c is an atypical Hsp40 which may lack the capability to interact with PfHsp70-1. To characterise the role of PFF1010c, and …