Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"HOXB13"”.
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Germline HOXB13 G84E Mutation Inhibits MEIS1-HOXB13 Driven Tumor Suppression in Prostate Cancer
… in the developmental transcription factor HOXB13 are nonspecifically associated with early onset and potentially rapid progression of prostate cancer, with no confirmation. The G84E mutation on HOXB13 was studied in the context of HOXB13’s tumor suppressive co-transcription factor, MEIS1, …
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A Comprehensive Genetic Risk Model for the Prediction of Future Prostate Cancer
… of the PCa risks associated with rare HOXB13, BRCA1 and BRCA2 PVs. Through systematic review and meta-analysis of 20 publications, I estimated a pooled PCa relative risk (RR) of 3.42 (95% confidence interval [CI] 2.81-4.17) for HOXB13 G84E carriers. Based on complex segregation analysis …