Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2145 for “"HOMEOSTASIS"”.
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Redox Homeostasis in Cyanobacteria
… many pathways involved in maintenance of redox homeostasis in cyanobacteria. Therefore, we also aimed to determine whether these pathways function cooperatively to ameliorate damage from ROS. Several flavodiiron: Flv) proteins have been identified in Synechocystis 6803 that are involved in …
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Calcium homeostasis in Pichia pastoris
… heterologous protein expression, and calcium homeostasis in P. pastoris . The divalent cations calcium and magnesium are responsible for diverse roles in in the function of the cells in eukaryotes. Although it is known that calcium is responsible for many biological functions in eukaryotes, …
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Calcium homeostasis in Escherichia coli
… eukaryotic cells, little is known about calcium homeostasis in bacteria at the physiological and molecular level. No calcium influx gene has been identified so far. This dissertation focuses on calcium regulation of gene expression by (i) determining the effects of elevated and depleted calcium …
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Imaging Chloride Homeostasis in Neurons
… activity. The study of their homeostasis requires simultaneous measurements in vivo in multiple neurons. Combining random mutagenesis screening, protein engineering and two-photon-imaging this thesis work led to the discovery of new chloride-sensitive GFP mutants and to the …
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Circadian Regulation of Protein Homeostasis
… translation and abundance affects protein homeostasis, maintenance of which is crucial for cell viability. In this thesis, I report the investigation of post-transcriptional temporal control of protein abundance, and the interplay between protein homeostasis and the circadian clock. I was …
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Regulation of Liver Homeostasis and Regeneration
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Natural Genetic Variation Affecting Calcium Homeostasis
… for identification of individual variation in Ca homeostasis and personalized dietary recommendations.</p>
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Magnesium homeostasis in the mammalian heart
… and extracellular cationic control of Mg2+ homeostasis in the rat heart. Subsequently, the effects of dietary magnesium on the magnesium, calcium, sodium and potassium content of the heart (and other tissues) in young rats is also investigated. Perfusion of the isolated heart with elevated …
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Risk homeostasis theory in simulated environments
… methodology for the investigation of risk homeostasis theory (RHT). It is argued that the current methodologies of the pseudo-experimental design and post hoc analysis of road-traffic accident data both have their limitations, and that the newer 'game' type simulation exercises are also, …
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Lipid metabolism and small intestine homeostasis
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01
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Homeostasis of primary and secondary metabolites
The student, Philip Olivares, submitted this Dissertation for approval on 2019-03-11 at 16:15.
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Lens calcium homeostasis and selenite cataract
A 3- to 5-fold increase in Ca2+ accompanies cataract formation induced by selenite. The mechanism of selenite cataractogenesis involves calcium activation of calpain with subsequent proteolysis within the lens nucleus. This study was undertaken to investigate the biochemical mechanisms that lead to …
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Macrophage-mediated regulation of joint homeostasis
… and IL-10-associated mechanisms of joint homeostasis lost in OA. Finally, using an equine model of synovitis, the last study investigated the response of normal and inflamed joints to autologous BMNC injection. Inflamed joints treated with BMNC showed gross and analytical improvements in …
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EPIGENETIC MODIFICATIONS REGULATING LIVER HOMEOSTASIS AND TUMORIGENESIS
… to maintain the liver metabolism and its homeostasis. Mechanistically, ARID1A loss induced chronic inflammation and, probably indirectly, genomic instability with the upregulation of the interferon pathway due to an increase of micronuclei. This statement imposed a selective pressure which …
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Geroprotective and antineoplastic functions of protein homeostasis
La homeostasis proteica, o proteostasis, comprende una compleja red molecular encargada de mantener la estabilidad del proteoma, controlando la conformación, localización y concentración de proteínas dentro de las células. Su alteración afecta al correcto funcionamiento de las células y está …
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Developmental signaling pathways in adult energy homeostasis
… involved in tissue maintenance and adult energy homeostasis. Furthermore, dysfunction of these signaling pathways results in human diseases such as cancer. An in depth understanding of how developmentally important signaling pathways function in the adult will provide mechanistic insights into …
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Iron and Manganese Homeostasis in Marine Bacteria
… were made on the mechanisms of Mn and Fe homeostasis in the marine α‐proteobacterium Ruegeria pomeroyi (the main species studied here), and in other important marine bacteria. R. pomeroyi lacks most of the known Fe uptake systems, including TonB and outer‐membrane receptors, but has a …
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Cellular Ensembles in Alveolar Homeostasis and Repair
… AT2s are still able to maintain tissue homeostasis and achieve efficient repair after injury. However, the underlying mechanisms of stem cell activation, injury response, and subsequent cell-cell communication signals mediating resolution of injury and restoration of alveolar homeostasis …
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Autophagy and Lipid Homeostasis in C. elegans
… the fundamental mechanisms that underlie lipid homeostasis in an intact organism. We discovered that autophagy gene activity (unc-51/ULK1/2, bec-1/BECN1, vps-34/VPS34, and lgg-1/LC3I) is required for neutral lipid accumulation during development in C. elegans. Moreover, long-lived, daf-2/InR and …
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Factors Affecting Manganese Homeostasis in the Chick
Plant and animal sources of manganese (Mn) are, for the most part, unavailable to the chick. Corn (C), soybean meal (SBM), fish meal (FM) and wheat bran (WB) reduced tissue Mn concentrations when added to a purified phytate- and fiber-free diet. Although these feed ingredients contain significant …
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