Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"HNF4alpha"”.
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Characterisation of the potentially diverse transcriptional regulatory mechanisms of human coagulation PZ gene.
… binding of hepatocyte nuclear factor 4 alpha (HNF4alpha), with the proximal site also reported by Sugawara and colleagues. Although both sites showed specific binding of protein only the protein binding the proximal site was confirmed as being HNF4alpha. The importance of HNF4alpha was further …
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Age-Associated Hepatic Drug Transporter Expression and Its Implications for Pediatric Pharmacotherapyflexibility affect DNA topoisomerase I function
… X receptor (FXR), and hepatic nuclear factor 4a (HNF4alpha). Our study revealed lower gene expression of MDR1/P-gp and MRP2 in the early infant period of development. We also identified a lower protein expression of MRP2 in the early infant period. For the nuclear receptors, we found significantly …
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O-GlcNAcylation: A key regulator of hepatic proliferation and differentiation
O-GlcNAcylation is a posttranslational modification involved in various physiological processes, including development, regeneration, inflammation, proliferation, metabolism, and pathogenesis of various diseases. O-GlcNAcylation is regulated by two enzymes, O-GlcNAc transferase (OGT), which adds a …