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Showing 1 to 3 of 3 for “"HNF-4"”.

  1. Characterization of the FTF/HNF-4 Sites Within the 7Alpha- and the 12Alpha-Hydroxylase Promoters Involved in the Bile Acid-Mediated Transcription of their Regulation

    … the transcription of the 7α-hydroxylase gene was HNF-4 since then many nuclear receptors have been identified that are involved in regulating the 7α- and 12α-hydroxylase genes. Among them the most important ones are FTF and HNF-4 which has been shown to play crucial roles in the transcription and …

    vcu Repository record for Characterization of the FTF/HNF-4 Sites Within the 7Alpha- and the 12Alpha-Hydroxylase Promoters Involved in the Bile Acid-Mediated Transcription of their Regulation (opens in a new tab)

  2. Identification and Characterization of Transcriptional Regulatory Elements for Liver-Specific Expression of Rabbit CYP2C Genes

    … factor hepatocyte nuclear factor 4 (HNF-4), since it was recognized by a nuclear protein with the same tissue distribution, DNA binding specificity and immunochemical reactivity as those of HNF-4. The CYP2C2 promoter-luciferase constructs containing either a native or an authentic …

    uiuc Repository record for Identification and Characterization of Transcriptional Regulatory Elements for Liver-Specific Expression of Rabbit CYP2C Genes (opens in a new tab)

  3. Exploring the Grey Zone between Type 1 and Type 2 Diabetes

    … as the cause of different forms of MODY, i.e. HNF-4 (MODY 1), glucokinase (GCK) (MODY 2), HNF-1 (MODY 3), IPF1 (MODY 4), HNF-1ß, formerly TCF2 (MODY 5) and NeuroD1 (MODY6). The goal of this thesis was to genetically dissect autoimmune (T1D and LADA) and non-autoimmune (T2D and MODY) diabetes in …

    lund Repository record for Exploring the Grey Zone between Type 1 and Type 2 Diabetes (opens in a new tab)