Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"HMQC"”.
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Naturstoffe aus Färbe- und Heilpflanzen
… und TOCSY, den heteronuklearen Experimenten HMQC und HMBC sowie den kombinierten NMR-Experimenten HMQC-COSY und HMQC-TOCSY vorgenommen. Die Anordnung der axial- und äquatorialständigen Protonen der Aglyca wurde mittels ROESY- oder NOESY-Messungen ermittelt. Auch die interglycosidischen …
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Antiproliferative Natural Products from the Madagascar Rainforest
… 1D and 2D NMR experiments, including COSY, HSQC/HMQC, HMBC, and ROESY/NOESY sequences, mass spectrometry, and chemical conversion. In addition, ten known compounds were obtained from five of the extracts. Studies on the remaining extracts were suspended due to various reasons. A multi-step …
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The application of nuclear magnetic resonance in the structural elucidation of natural products
… The Heteronuclear Multiple Quantum Coherence (HMQC) experiment offered greater sensitivity on small sample quantities whilst the long range Heteronuclear Correlation (HETCOR) and Heteronuclear Multiple Bond Coherence (HMBC) experiments were essential for complete assignment of the quaternary …
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Insektizide Rocaglamid-Derivate und Verwandte Verbindungen aus Aglaia-Arten (Meliaceae)
… (darunter 2D-Experimente wie H-H-COSY, HMQC, HMBC und ROESY) sowie durch Massenspektrometrie. Die Untersuchungen zur Struktur-Wirkungs-Beziehung ergaben für die Rocaglamide V, Z und AA eine starke insektizide Aktivität gegenüber Raupen von S. littoralis mit LC50- und EC50-Werten von 2.0 …
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Isolation and Structure Elucidation of Anticancer and Antimalarial Natural Products
… and 2D NMR spectroscopy including COSY, HASQC, HMQC, HMBC, and NOESY sequences, mass spectrometry, UV, IR, ECD, optical rotation, and chemical conversions. In addition, ten known compounds were isolated from another five of the extracts, while studies on the remaining extracts were suspended due …
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Novel ferrocenyl benzoyl peptide esters as anti-cancer agents and ferrocenoyl self assembled monolayers as anion sensors
… techniques including: 1H, 13C, DEPT 135 and HMQC NMR in addition to IR, UV-Vis, MS and CV. The biological effects of orientation around the central benzoyl moiety, increasing peptide chain length and lipophilicity were investigated for the N-(ferrocenyl)benzoyl peptide esters. The most active …
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3-(R)-Hydroxysäuren als Produkte selektiven Fettsäureabbaus
… (1H-NMR, 13C-NMR, 13C-DEPT, H/H-COSY, HMQC, HMBC). Linolsäure wurde von Stenotrophomonas maltophilia zu 3-Hydroxy-Z6-dodecensäure, 3-Hydroxy-Z5,Z8-tetradecadiensäure und 3-Hydroxy-Z7,Z10-hexadecadiensäure umgesetzt. In einem anschließenden Substratscreening wurden 32 Verbindungen als …
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Spectroscopic and synthetic studies relating to a dirhodium hydroformylation catalyst
… and <sup>31</sup>P, and 2D COSY, HMBC, and HMQC were employed and indicated the formation of the key catalyst, [rac-Rh<sub>2</sub>H<sub>2</sub>(μ-CO)<sub>2</sub>(CO)<sub>4</sub>(et,ph-P4)]<sup>2+</sup>, 4, and a number of other Rh-phosphine species on and off the catalytic cycle. Detailed …
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Naturstoffe aus Heilpflanzen und marinen Organismen
… 1H,1H-COSY und den heteronuklearen Experimenten HMQC und HMBC ermittelt. Die relative Konfiguration wurde durch die Auswertung von ROESY-Spektren festgelegt. Die Analyse der Steroidgemische erfolgte nach Trimethylsilylierung mittels GC-MS-Messungen. Aus den Heilpflanzen Zizyphus spina-christi und …
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Antimalarial activity of hypoxis colchicifolia, bak, mimusops caffra, E. Mey. ex A.DC and mimusops obtusifolia, lam from South Africa
… application of 2D-NMR (1H-1H, 13C, DEPT, COSY, HMQC, HMBC and NOESY) and infrared (IR). The preliminary phytochemical analysis of plants’ extracts revealed the presence mainly of saponins, tannins, alkaloids and flavonoids. Methanol extracts of the plants exhibited strong scavenging of …
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STRUCTURE–ACTIVITY RELATIONSHIP STUDIES OF HYBRID ANTITUMOR AGENTS FOR THE TREATMENT OF NON-SMALL CELL LUNG CANCER
… study using time-dependent 1H NMR and 2-D HMQC NMR spectroscopy, as well as in-line liquid chromatography–electro-spray mass spectrometry (LC–ESMS). A cellular imaging study using confocal fluorescence microscopy was performed to study the subcellular distribution of complex 54. The results …
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Supramolecular Ru II, Pt II Complexes Bridged by 2,3,5,6-tetrakis(2-pyridyl)pyrazine (tppz)
… ¹⁹⁵Pt-NMR and 2D COSY, NOESY and ¹⁹⁵Pt-¹H HMQC, as well as dynamic ¹H-NMR at variable temperatures. The bi- and tri-metallic complexes are crystallized in the chiral space group of C2/c and P21/c as racemic compounds. The interconversion of the three steroisomers, M-M, P-P and M-P of …
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13C PEG as an In Vivo Macromolecular Probe for MRI and Biophysical Studies of Detergent-Peptide and Detergent-Detergent Interactions using NMR
In the first part of this thesis, a new platform technology is demonstrated for the direct in vivo observation and quantification of macromolecular constituents, such as proteins and drug delivery systems, using 1H MRI. To overcome sensitivity challenges, a 28 kDa non-immunogenic tag is employed, …
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Isolierung, Identifizierung und Partialsynthese von Pflanzeninhaltsstoffen aus Croton flavens L.
… der 1H-, 13C-, DEPT-, APT-, HH-COSY-, NOE-, HMQC- und HMBC-NMR-Spektren. Elf Substanzen gehören der Stoffklasse der Alkaloide an. Ein Tetrahydroprotoberberin-Grundgerüst besitzen Scoulerin (1) und Coreximin (2). Die beiden Substanzen unterscheiden sich nur in der Anordnung einer …
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Effects of Cisplatin Analog Size on the Reaction with DNA Bases
<p>Cancer is the second leading cause of death in the United States. Cisplatin is one of the well-known anti-cancer agents used to treat testicular and ovarian cancers. It mainly binds to the DNA bases, which leads to cell death. The cytotoxic activity of the cisplatin analogs is due to the …
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Structure Elucidation of Bioactive Compounds Isolated from Endophytes of Alstonia scholaris and Acmena graveolens
Alstonia scholaris is an evergreen tree native to Southeast Asia and Australia. It is commonly used as a medicinal plant throughout these regions. In the present study, an endophyte of the genus Xylaria was isolated from a stem of Alstonia scholaris, its mycelia and exudate extracted, and the …