Global ETD Search
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Showing 1 to 2 of 2 for “"HMG-CoA Lyase"”.
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Characterization of Amino Acid tRNA Ligases using the Analytical Ultracentrifuge
… with a resolution of 8 A. In Paper V the enzyme HMG-CoA lyase was investigated. The activity of this enzyme is found in Rhodospirillum rubrum cells grown anaerobically in the light with leucine as the carbon source. A 1.2 kb long DNA segment from R. rubrum has been sequenced and includes the …
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3-Hydroxy-3-methylglutaryl-coenzyme A lyase: investigation of cysteines mediating intersubunit disulfide formation and regulation by thiol/disulfide exchange and discovery of an extramitochondrial homolog
3-Hydroxy-3-methylglutaryl-Coenzyme A lyase catalyzes the cleavage of 3-hydroxy- 3-methylglutaryl-Coenzyme A into acetoacetate and acetyl-Coenzyme A, a key reaction in ketogenesis and leucine catabolism. Previous work prompted the hypothesis that in the absence of reductant, cysteine 323 forms a …