Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"HMC-1 cells"”.
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Regulation Mechanisms of TIM-3 expression in Jurkat T cells and HMC-1 cells
… 사용한 결과 Jurkat T 세포와 인간 CD4+ T 세포에서는 MEK 경로, HMC-1 세포에서는 MEK 경로와 SMAD 의존적 경로가 TIM-3 발현에 중요하게 작용함을 밝혔다. 또한 T 세포에서 TIM-3 발현 조절에 중요하게 작용하는 promoter 부분을 찾기 위해 다양한 길이의 TIM-3 promoter를 포함하는 luciferase reporter vector를 제작하여 luciferase 활성도를 측정하였다. 그 결과 TIM-3 promoter -892/-870과 -144/-121 부분이 자극에 의한 …
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Effects of IL-33 on the interaction between HMC-1 cells and human airway smooth muscle cells
… airways inflammation. The interaction of mast cells and human airway smooth muscle (HASM) cells play an important role in the characteristic pathological processes involved with asthma. The recently discovered cytokine, interleukin 33 (IL-33), is thought to play an important role in a variety …
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Regulation of TIM-3 Expression in Mast cells and Monocytes
… ligand galectin-9 has been demonstrated in mast cells, the transcriptional regulation of these molecules has not been well explored. Considering the emerging role of mast cells in host defense, I studied the effect of various cytokines, a TLR agonist or FcεR stimulation on transcription levels of …
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Genetic effect of histamine N-methyltransferase (HNMT) polymorphism on chronic urticaria with aspirin hypersensitivity
… that with haplotype 3 (-465C/-413T) construct in HMC-1 cell line (p < 0.05). Transcription factor, serum response accessory protein-1 (SAP-1), was bound to the HNMT -465C allele probe (-477/-454) with higher affinity than that of the -465T allele probe. The 939A>G polymorphism was significantly …
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Genetic Polymorphism of Prostanoid Receptors, CRTH2 and TBXA2R in Aspirin Hypersensitivity
… receptor molecule which is expressed on Th2 cells including other allergy related cells like eosinophils, basophils and monocytes. Its importance in inflammatory cell activation and recruitment in vitro and in vivo has been continuously reported in several studies. Considering the fact that …